Evidence map›Paper›PMID 26218382›Full record

ArticlePlastic and reconstructive surgery2015

Optimizing Hybrid Occlusion in Face-Jaw-Teeth Transplantation: A Preliminary Assessment of Real-Time Cephalometry as Part of the Computer-Assisted Planning and Execution Workstation for Craniomaxillofacial Surgery.

Ryan J Murphy, Ehsan Basafa, Sepehr Hashemi, Gerald T Grant, Peter Liacouras, Srinivas M Susarla, Yoshito Otake, Gabriel Santiago, Mehran Armand, Chad R Gordon

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ryan J MurphyLaurel, Baltimore, and Bethesda, Md.; and Boston, Mass. From the Johns Hopkins University Applied Physics Laboratory; the Department of Mechanical Engineering, Johns Hopkins University; the Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine; Craniofacial Imaging, Naval Postgraduate Dental School, 3D Medical Center, and the Department of Ear, Nose, and Throat-Head and Neck Surgery, Walter Reed National Medical Center; and Harvard School of Dental Medicine/Harvard Medical School.
Ehsan Basafa
Sepehr Hashemi
Gerald T Grant
Peter Liacouras
Srinivas M Susarla
Yoshito Otake
Gabriel Santiago
Mehran Armand
Chad R Gordon

Funding

Institute for Clinical and Translational ResearchUL1TR000424 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$6.0M
Computer-Assisted Orthopaedic Surgery with Intra-Operative Biomechanical GuidanceR01EB006839 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI ARMAND, MEHRAN · 2007 to 2010
$1.5M
Preoperative Planning of FemoroplastyR21AR063815 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI ARMAND, MEHRAN · 2013 to 2014
$346k
NCATS NIH HHS UL1 TR000424NCATS NIH HHS UL1TR000424-06NIAMS NIH HHS R21 AR063815NIBIB NIH HHS R01 EB006839
6 · The paper itself

Abstract

backgroundThe aesthetic and functional outcomes surrounding Le Fort-based, face-jaw-teeth transplantation have been suboptimal, often leading to posttransplant class II/III skeletal profiles, palatal defects, and "hybrid malocclusion." Therefore, a novel technology-real-time cephalometry-was developed to provide the surgical team instantaneous, intraoperative knowledge of three-dimensional dentoskeletal parameters.

methodsMock face-jaw-teeth transplantation operations were performed on plastic and cadaveric human donor/recipient pairs (n = 2). Preoperatively, cephalometric landmarks were identified on donor/recipient skeletons using segmented computed tomographic scans. The computer-assisted planning and execution workstation tracked the position of the donor face-jaw-teeth segment in real time during the placement/inset onto recipient, reporting pertinent hybrid cephalometric parameters from any movement of donor tissue. The intraoperative data measured through real-time cephalometry were compared to posttransplant measurements for accuracy assessment. In addition, posttransplant cephalometric relationships were compared to planned outcomes to determine face-jaw-teeth transplantation success.

resultsCompared with postoperative data, the real-time cephalometry-calculated intraoperative measurement errors were 1.37 ± 1.11 mm and 0.45 ± 0.28 degrees for the plastic skull and 2.99 ± 2.24 mm and 2.63 ± 1.33 degrees for the human cadaver experiments. These results were comparable to the posttransplant relations to planned outcome (human cadaver experiment, 1.39 ± 1.81 mm and 2.18 ± 1.88 degrees; plastic skull experiment, 1.06 ± 0.63 mm and 0.53 ± 0.39 degrees).

conclusionBased on this preliminary testing, real-time cephalometry may be a valuable adjunct for adjusting and measuring "hybrid occlusion" in face-jaw-teeth transplantation and other orthognathic surgical procedures.

Indexed as

AgedAged, 80 and overAnatomic LandmarksCadaverCephalometryCraniofacial AbnormalitiesDiagnosis, Computer-AssistedFaceFacial TransplantationFemaleHumansImaging, Three-DimensionalJaw AbnormalitiesOral Surgical ProceduresOrthognathic Surgical ProceduresSensitivity and Specificity

Identifiers

PMID26218382
PMCPMC4758939

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