Evidence map›Paper›PMID 26217818›Full record

ArticleData in brief2015

Quantitative analysis of the myelin g-ratio from electron microscopy images of the macaque corpus callosum.

Nikola Stikov, Jennifer S W Campbell, Thomas Stroh, Mariette Lavelée, Stephen Frey, Jennifer Novek, Stephen Nuara, Ming-Kai Ho, Barry J Bedell, Robert F Dougherty and 9 more

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. MyelinASN neuro · 2026
    Article
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  11. Advanced Diffusion MR Imaging for Multiple Sclerosis in the Brain and Spinal Cord.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Nikola StikovMontreal Neurological Institute, McGill University, Montreal, Canada ; École Polytechnique de Montréal, Montréal, Canada.
Jennifer S W CampbellMontreal Neurological Institute, McGill University, Montreal, Canada.
Thomas StrohMontreal Neurological Institute, McGill University, Montreal, Canada.
Mariette LaveléeMontreal Neurological Institute, McGill University, Montreal, Canada.
Stephen FreyMontreal Neurological Institute, McGill University, Montreal, Canada.
Jennifer NovekMontreal Neurological Institute, McGill University, Montreal, Canada.
Stephen NuaraMontreal Neurological Institute, McGill University, Montreal, Canada.
Ming-Kai HoMontreal Neurological Institute, McGill University, Montreal, Canada.
Barry J BedellMontreal Neurological Institute, McGill University, Montreal, Canada.
Robert F DoughertyStanford University, Stanford, CA, United States.
Ilana R LeppertMontreal Neurological Institute, McGill University, Montreal, Canada.
Mathieu BoudreauMontreal Neurological Institute, McGill University, Montreal, Canada.
Sridar NarayananMontreal Neurological Institute, McGill University, Montreal, Canada.
Tanguy DuvalÉcole Polytechnique de Montréal, Montréal, Canada.
Julien Cohen-AdadÉcole Polytechnique de Montréal, Montréal, Canada.
Paul-Alexandre PicardÉcole supérieure d׳ingénieurs en génie électrique, Rouen, France.
Alicja GaseckaUniversité Laval, Quebec City, Canada.
Daniel CôtéUniversité Laval, Quebec City, Canada.
G Bruce PikeMontreal Neurological Institute, McGill University, Montreal, Canada ; Hotchkiss Brain Institute and Department of Radiology, University of Calgary, Calgary, Alberta, Canada.
Montreal Neurological Institute and Hospital · CAMcGill University · CAPolytechnique Montréal · CAUniversité Laval · CAÉcole Supérieure d'Ingénieurs en Génie Électrique · FRStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We provide a detailed morphometric analysis of eight transmission electron micrographs (TEMs) obtained from the corpus callosum of one cynomolgus macaque. The raw TEM images are included in the article, along with the distributions of the axon caliber and the myelin g-ratio in each image. The distributions are analyzed to determine the relationship between axon caliber and g-ratio, and compared against the aggregate metrics (myelin volume fraction, fiber volume fraction, and the aggregate g-ratio), as defined in the accompanying research article entitled 'In vivo histology of the myelin g-ratio with magnetic resonance imaging' (Stikov et al., NeuroImage, 2015).

Identifiers

PMID26217818
PMCPMC4510539
OpenAlexW577586447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.