Evidence map›Paper›PMID 26217674›Full record

ArticleNeurophotonics2015

Optical coherence tomography for cross-sectional imaging of neural activity.

Yi-Jou Yeh, Adam J Black, David Landowne, Taner Akkin

Open access · bronzeAbstract read
In one paragraph

Article in Neurophotonics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yi-Jou YehUniversity of Minnesota , Department of Electrical and Computer Engineering, Minneapolis, Minnesota 55455, United States ; University of Minnesota , Department of Biomedical Engineering, 312 Church Street S.E., Minneapolis, Minnesota 55455, United States.
Adam J BlackUniversity of Minnesota , Department of Biomedical Engineering, 312 Church Street S.E., Minneapolis, Minnesota 55455, United States.
David LandowneUniversity of Miami , Department of Physiology and Biophysics, Miami, Florida 33101, United States.
Taner AkkinUniversity of Minnesota , Department of Biomedical Engineering, 312 Church Street S.E., Minneapolis, Minnesota 55455, United States.
University of Minnesota · USTwin Cities Orthopedics · USUniversity of Miami · US

Funding

Depth-resolved Optical Imaging of Neural Action PotentialsR01EB012538 · NIBIB · UNIVERSITY OF MINNESOTA · PI AKKIN, TANER · 2011 to 2014
$1.3M
NIBIB NIH HHS R01 EB012538
6 · The paper itself

Abstract

We report a functional optical coherence tomography cross-sectional scanner to detect neural activity using unmyelinated nerves dissected from squid. The nerves, unstained or stained with a voltage-sensitive dye, were imaged in a nerve chamber. Transient phase changes from backscattered light were detected during action potential propagation. The results show that the scanner can provide high spatiotemporal resolution cross-sectional images of neural activity ([Formula: see text]; [Formula: see text]; [Formula: see text] in [Formula: see text]). The advantage of this method compared to monitoring a single depth profile [Formula: see text] is a dramatic increase in the number of available sites that can be measured in two spatial dimensions [Formula: see text] with lateral scanning; therefore, the study demonstrates that two-dimensional monitoring of small-scale functional activity would also be feasible.

Indexed as

action potentialsfunctional imagingphase measurementvoltage sensitive dye imaging

Identifiers

PMID26217674
PMCPMC4509668
OpenAlexW1960524559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.