Evidence map›Paper›PMID 26217361›Full record

ArticleFrontiers in plant science2015

Molecular phenotyping of plant single cell-types enhances forward genetic analyses.

John Schiefelbein

Abstract read
In one paragraph

Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John SchiefelbeinDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan , Ann Arbor, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in the isolation of single cell-types in plants provides an opportunity to conduct detailed analyses of their molecular characteristics at high resolution. This kind of cell-type specific molecular phenotyping is likely to enhance forward genetics studies to dissect the effect of mutations and thereby aid gene function assignment. Recent experimental results support this view, demonstrating that different cell-types exhibit substantial variation in transcript, protein, and metabolite accumulation and these molecular phenotypes are often sensitive to genetic and environmental alterations. The use of single cell-type molecular phenotyping approach to define plant gene function is most amenable to cell-types with well-characterized molecular tools and isolation protocols.

Indexed as

cell biologygenetic analysismolecular phenotypemutanttranscriptomics

Identifiers

PMID26217361
PMCPMC4491599

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.