ReviewWorld journal of gastroenterology2015
Effects of Yttrium-90 selective internal radiation therapy on non-conventional liver tumors.
Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
- Liver Resection after Disease Control with Abemaciclib for Solitary Liver Metastasis from Breast Cancer: A Case Report.Surgical case reports · 2026Article
- Expanding the Scope of Interventional Oncology: Locoregional Therapies in Extrahepatic Malignancies.Cancers · 2025Review
- Yttrium-90 Transarterial Radioembolization of Primary Lung Cancer Metastases to the Liver.Journal of vascular and interventional radiology : JVIR · 2024Article
- Adrenocortical carcinoma: selective internal radiation therapy and liver metastases.Endocrine oncology (Bristol, England) · 2024Article
- Real-time in vivo dose measurement using ruby-based fibre optic dosimetry during internal radiation therapy.Physical and engineering sciences in medicine · 2023Article
- Breast cancer recurrence: factors impacting occurrence and survival.Irish journal of medical science · 2022Article
- A descriptive analysis of the characteristics, treatment response and prognosis of hepatic dominant solid tumors undergoing selective internal radiation therapy (SIRT).Journal of gastrointestinal oncology · 2022Article
- Realized tumor to normal ratios in hepatocellular carcinoma patients undergoing transarterial radioembolization: a retrospective evaluation.European radiology · 2022Article
- Metastatic disease to the liver: Locoregional therapy strategies and outcomes.World journal of clinical oncology · 2021Review
- Clinical Application of Trans-Arterial Radioembolization in Hepatic Malignancies in Europe: First Results from the Prospective Multicentre Observational Study CIRSE Registry for SIR-Spheres Therapy (CIRT).Cardiovascular and interventional radiology · 2021Observational
- Clinical Application of Radioembolization in Hepatic Malignancies: Protocol for a Prospective Multicenter Observational Study.JMIR research protocols · 2020Article
- Palliative TACE for hepatic metastases of chromophobe renal cell carcinoma.BMJ case reports · 2019Article
- Initial clinical radiological findings and staging to predict prognosis of primary hepatic angiosarcoma: A retrospective analysis.PloS one · 2019Article
- Hepatic Progression-free and Overall Survival After Regional Therapy to the Liver for Metastatic Melanoma.American journal of clinical oncology · 2018Article
- Selective internal radiation therapy: an effective treatment for hormonal syndromes in pancreatic neuroendocrine tumors.Hepatic oncology · 2018Article
- Hepatic artery infusion of melphalan in patients with liver metastases from ocular melanoma.Journal of surgical oncology · 2018Article
- From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing world.World journal of gastroenterology · 2017Review
- Update on Treatment Options for Advanced Bile Duct Tumours: Radioembolisation for Advanced Cholangiocarcinoma.Current oncology reports · 2017Review
- Transarterial Yttrium-90 Radioembolization Treatment of Patients with Liver-Dominant Metastatic Renal Cell Carcinoma.Journal of vascular and interventional radiology : JVIR · 2017Article
- Treatment of Non-Colorectal Liver Metastases.Viszeralmedizin · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The liver is a common site of metastasis, with essentially all metastatic malignancies having been known to spread to the liver. Nearly half of all patients with extrahepatic primary cancer have hepatic metastases. The severe prognostic implications of hepatic metastases have made surgical resection an important first line treatment in management. However, limitations such as the presence of extrahepatic spread or poor functional hepatic reserve exclude the majority of patients as surgical candidates, leaving chemotherapy and locoregional therapies as next best options. Selective internal radiation therapy (SIRT) is a form of catheter-based locoregional cancer treatment modality for unresectable tumors, involving trans-arterial injection of microspheres embedded with a radio-isotope Yttrium-90. The therapeutic radiation dose is selectively delivered as the microspheres permanently embed themselves within the tumor vascular bed. Use of SIRT has been conventionally aimed at treating primary hepatic tumors (hepatocellular carcinoma) or colorectal and neuroendocrine metastases. Numerous reviews are available for these tumor types. However, little is known or reviewed on non-colorectal or non-neuroendocrine primaries. Therefore, the aim of this paper is to systematically review the current literature to evaluate the effects of Yttrium-90 radioembolization on non-conventional liver tumors including those secondary to breast cancer, cholangiocarcinoma, ocular and percutaneous melanoma, pancreatic cancer, renal cell carcinoma, and lung cancer.
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