ArticleProceedings of the National Academy of Sciences of the United States of America2015
Highly permeable artificial water channels that can self-assemble into two-dimensional arrays.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Rapid Water Permeation by Aramid Foldamer Nanochannels With Hydrophobic Interiors.Angewandte Chemie (International ed. in English) · 2025Article
- Microbial membrane transport proteins and their biotechnological applications.World journal of microbiology & biotechnology · 2024Review
- Review
- Differences in water and vapor transport through angstrom-scale pores in atomically thin membranes.Nature communications · 2022Article
- Pillar[n]arene-Mimicking/Assisted/Participated Carbon Nanotube Materials.Materials (Basel, Switzerland) · 2022Review
- Selective and rapid water transportation across a self-assembled peptide-diol channelChemical science · 2022Article
- Molecular-Level Control over Ionic Conduction and Ionic Current Direction by Designing Macrocycle-Based Ionomers.JACS Au · 2022Article
- Article
- ScatteringNanoscale advances · 2021Article
- Water Transport and Ion Diffusion Investigation of an Amphotericin B-Based Channel Applied to Forward Osmosis: A Simulation Study.Membranes · 2021Article
- Foldamer-based ultrapermeable and highly selective artificial water channels that exclude protons.Nature nanotechnology · 2021Article
- Water Dynamics in a Peptide-appended Pillar[5]arene Artificial Channel in Lipid and Biomimetic Membranes.Frontiers in chemistry · 2021Article
- Porous organic cages as synthetic water channels.Nature communications · 2020Article
- Water in Nanopores and Biological Channels: A Molecular Simulation Perspective.Chemical reviews · 2020Review
- Water-ion permselectivity of narrow-diameter carbon nanotubes.Science advances · 2020Article
- Rapid fabrication of precise high-throughput filters from membrane protein nanosheets.Nature materials · 2020Article
- Artificial water channels enable fast and selective water permeation through water-wire networks.Nature nanotechnology · 2020Article
- Article
- Article
- PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore.Nature communications · 2018Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Bioinspired artificial water channels aim to combine the high permeability and selectivity of biological aquaporin (AQP) water channels with chemical stability. Here, we carefully characterized a class of artificial water channels, peptide-appended pillar[5]arenes (PAPs). The average single-channel osmotic water permeability for PAPs is 1.0(± 0.3) × 10(-14) cm(3)/s or 3.5(± 1.0) × 10(8) water molecules per s, which is in the range of AQPs (3.4 ∼ 40.3 × 10(8) water molecules per s) and their current synthetic analogs, carbon nanotubes (CNTs, 9.0 × 10(8) water molecules per s). This permeability is an order of magnitude higher than first-generation artificial water channels (20 to ∼ 10(7) water molecules per s). Furthermore, within lipid bilayers, PAP channels can self-assemble into 2D arrays. Relevant to permeable membrane design, the pore density of PAP channel arrays (∼ 2.6 × 10(5) pores per μm(2)) is two orders of magnitude higher than that of CNT membranes (0.1 ∼ 2.5 × 10(3) pores per μm(2)). PAP channels thus combine the advantages of biological channels and CNTs and improve upon them through their relatively simple synthesis, chemical stability, and propensity to form arrays.
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