Evidence map›Paper›PMID 26216565›Full record

ArticleHuman psychopharmacology2015

Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK.

Lynn T Singer, Derek G Moore, Meeyoung O Min, Julia Goodwin, John J D Turner, Sarah Fulton, Andrew C Parrott

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lynn T SingerCase Western Reserve University, Cleveland, Ohio, USA.
Derek G MooreThe University of East London, London, UK.
Meeyoung O MinCase Western Reserve University, Cleveland, Ohio, USA.
Julia GoodwinThe University of East London, London, UK.
John J D TurnerThe University of East London, London, UK.
Sarah FultonCase Western Reserve University, Cleveland, Ohio, USA.
Andrew C ParrottSwansea University, Swansea, UK.
Case Western Reserve University · USUniversity of East London · GBSwansea University · GB

Funding

Developmental Outcomes of Prenatal Exposure to MDMA ('E*R01DA014910 · NIDA · CASE WESTERN RESERVE UNIVERSITY · PI SINGER, LYNN T · 2001 to 2005
$2.8M
NIDA NIH HHS DA14910-01NIDA NIH HHS R01 DA014910
6 · The paper itself

Abstract

objectiveThis paper aims to review findings from a longitudinal study of prenatal methylenedioxymethamphetamine (MDMA, "ecstasy") on infant development.

methodsIn a prospective, longitudinal cohort design, we followed 28 MDMA-exposed and 68 non-MDMA-exposed infants from birth to 2 years of age. Women recruited voluntarily into a study of recreational drug use during pregnancy were interviewed to obtain type, frequency, and amount of recreational drug use. Their children were followed for a 2-year period after birth. A large number of drug and environmental covariates were controlled. Infants were seen at 1, 4, 12, 18, and 24 months using standardized normative tests of mental and motor development.

resultsThere were no differences between MDMA-exposed and non-MDMA-exposed infants at birth except that MDMA-exposed infants were more likely to be male. Motor delays were evident in MDMA infants at each age and amount of MDMA exposure predicted motor deficits at 12 months in a dose-dependent fashion.

conclusionsPrenatal MDMA exposure is related to fine and gross motor delays in the first 2 years of life. Follow-up studies are needed to determine long-term effects.

Indexed as

AdultAge FactorsChild DevelopmentDevelopmental DisabilitiesFemaleHallucinogensHumansInfantInfant, NewbornMaleN-Methyl-3,4-methylenedioxyamphetaminePregnancyPrenatal Exposure Delayed EffectsUnited KingdomHallucinogensN-Methyl-3,4-methylenedioxyamphetamineecstasyinfant developmentMDMAmethylenedioxymethamphetaminemotorprenatal

Identifiers

PMID26216565
PMCPMC5107979
OpenAlexW1679347963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.