Trial reportBMC oral health2015
Signs and symptoms associated with primary tooth eruption: a clinical trial of nonpharmacological remedies.
Trial report in BMC oral health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 58 citations in OpenAlex.
- Perception of parents/guardians about self-medication for oral problems in their children: a cross-sectional study in Brazilian parents/guardians.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Cytotoxic and antifungal effects of different teething oral gels: an in-vitro study.Head & face medicine · 2025Article
- A Comparative Analysis of Feeding Practices and Oral Immunity in Infants.Medicina (Kaunas, Lithuania) · 2025Article
- A Narrative Review on Advancing Pediatric Oral Health: Comprehensive Strategies for the Prevention and Management of Dental Challenges in Children.Children (Basel, Switzerland) · 2025Review
- A study of Facebook comments regarding amber teething necklaces: insights into public perception.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Article
- Knowledge and experiences of families regarding amber necklaces.BMC complementary medicine and therapies · 2023Article
- A questionnaire-based study of Paediatric Dentists' knowledge of teething signs, symptoms and management.BDJ open · 2022Article
- Symptoms of the Eruption of Permanent Teeth.International journal of environmental research and public health · 2022Article
- Owner-Implemented Functional Analyses and Reinforcement-Based Treatments for Mouthing in Dogs.Behavior analysis in practice · 2022Article
- Article
- Awareness of Lebanese Pediatricians regarding Children's Oral Health.International journal of clinical pediatric dentistryArticle
- Soothing Effect of an Edible Teether: A Pilot Study in Children during Primary Dentition Age.International journal of clinical pediatric dentistryArticle
- Exploring Parental Knowledge and Indigenous Practices for Infant Teething in Indian Population: A Cross-sectional Study.International journal of clinical pediatric dentistryArticle
- Evaluation of Levels of Proinflammatory Chemokines MIP-1α and MIP-1β in Gingival Crevicular Fluid of Primary, Mixed and Permanent Dentition.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate disturbances in primary tooth eruption and their management with nonpharmacological remedies.
methodsIn this nonrandomized clinical trial, 270 children aged between 8 and 36 months were selected and divided into 5 groups with 54 children initially enrolled in each group. The children were seen during an 8-day period during tooth eruption. At each appointment data were recorded from oral examination, tympanic temperature measurement and a questionnaire. The five methods used as remedies to reduce teething symptoms were: 1) cuddle therapy, 2) ice, 3) rubbing the gums, 4) teething rings and 5) food for chewing. Teething symptoms, the type of erupted tooth, symptoms of recovery and the mother's satisfaction with treatment were evaluated.
resultsTwo hundred and fifty four children (mean age 16 ± 7.2 months) completed the study. The most frequent teething symptoms were drooling (92%), sleep disturbances (82.3%) and irritability (75.6%). These symptoms were more pronounced in low birth weight children (p > 0.05). Canine eruption led to more loss of appetite than incisor (p = 0.033) or molars eruption (p = 0.014). Low grade increases in body temperature were observed only on the day of eruption (36.70 ± 0.39 °C), when body temperature was significantly different compared to the day before and the day after eruption (both p < 0.001). There was no significant correlation between fever as reported by mothers and temperature readings obtained by the investigators. The most favorable results for time to recovery and the mother's satisfaction were seen when teething rings were used, followed by cuddle therapy and rubbing the gums.
conclusionsThere was no association between teething and symptoms such as fever or diarrhea. Low birth weight children may have more teething symptoms. Teething rings, cuddle therapy and rubbing the gums were the most effective methods to reduce symptoms.
trial registrationIranian Registry of Clinical Trials: code IRCT201211127402N3.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.