ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2015
Validation of QTL for resistance to Aphanomyces euteiches in different pea genetic backgrounds using near-isogenic lines.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Comparative Genomics Provide Insight Into the Evolution of European Aphanomyces euteiches Strains.Genome biology and evolution · 2026Article
- Association genetics and genomic prediction for resistance to root rot in a diverse collection of Pisum sativum L.BMC plant biology · 2025Article
- QTL combinations associated with field partial resistance to Aphanomyces root rot in pea near-isogenic lines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Identification of Sources of Resistance to Aphanomyces Root Rot inPlants (Basel, Switzerland) · 2024Article
- Transcriptomic analysis identifies candidate genes for Aphanomyces root rot disease resistance in pea.BMC plant biology · 2024Article
- Fine mapping of Ae-Ps4.5, a major locus for resistance to pathotype III of Aphanomyces euteiches in pea.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Understanding the root of the problem for tackling pea root rot disease.Frontiers in microbiology · 2024Review
- Advanced backcross QTL analysis and comparative mapping with RIL QTL studies and GWAS provide an overview of QTL and marker haplotype diversity for resistance to Aphanomyces root rot in pea (Frontiers in plant science · 2023Article
- A fine-tuned defense at the pea root caps: Involvement of border cells and arabinogalactan proteins against soilborne diseases.Frontiers in plant science · 2023Review
- Pea Breeding for Resistance to Rhizospheric Pathogens.Plants (Basel, Switzerland) · 2022Review
- Identification of Novel Genes Associated with Partial Resistance to Aphanomyces Root Rot in Field Pea by BSR-Seq Analysis.International journal of molecular sciences · 2022Article
- A major-effect genetic locus, ApRVII, controlling resistance against both adapted and non-adapted aphid biotypes in pea.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Genomics Enabled Breeding Strategies for Major Biotic Stresses in Pea (Frontiers in plant science · 2022Review
- Mapping QTL associated with partial resistance to Aphanomyces root rot in pea (Pisum sativum L.) using a 13.2 K SNP array and SSR markers.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Omics resources and omics-enabled approaches for achieving high productivity and improved quality in pea (Pisum sativum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Identification of Candidate Cotton Genes Associated With Fiber Length Through Quantitative Trait Loci Mapping and RNA-Sequencing Using a Chromosome Segment Substitution Line.Frontiers in plant science · 2021Article
- The Effects of Domestication on Secondary Metabolite Composition in Legumes.Frontiers in genetics · 2020Review
- Construction, characteristics and high throughput molecular screening methodologies in some special breeding populations: a horticultural perspective.Journal of genetics · 2019Review
- Application of high-throughput amplicon sequencing-based SSR genotyping in genetic background screening.BMC genomics · 2019Article
- Identification and validation of major and minor QTLs controlling seed coat color inBreeding science · 2019Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageMarker-assisted backcrossing was used to generate pea NILs carrying individual or combined resistance alleles at main Aphanomyces resistance QTL. The effects of several QTL were successfully validated depending on genetic backgrounds. Quantitative trait loci (QTL) validation is an important and often overlooked step before subsequent research in QTL cloning or marker-assisted breeding for disease resistance in plants. Validation of QTL controlling partial resistance to Aphanomyces root rot, one of the most damaging diseases of pea worldwide, is of major interest for the future development of resistant varieties. The aim of this study was to validate, in different genetic backgrounds, the effects of various resistance alleles at seven main resistance QTL recently identified. Five backcross-assisted selection programs were developed. In each, resistance alleles at one to three of the seven main Aphanomyces resistance QTL were transferred into three genetic backgrounds, including two agronomically important spring (Eden) and winter (Isard) pea cultivars. The subsequent near-isogenic lines (NILs) were evaluated for resistance to two reference strains of the main A. euteiches pathotypes under controlled conditions. The NILs carrying resistance alleles at the major-effect QTL Ae-Ps4.5 and Ae-Ps7.6, either individually or in combination with resistance alleles at other QTL, showed significantly reduced disease severity compared to NILs without resistance alleles. Resistance alleles at some minor-effect QTL, especially Ae-Ps2.2 and Ae-Ps5.1, were also validated for their individual or combined effects on resistance. QTL × genetic background interactions were observed, mainly for QTL Ae-Ps7.6, the effect of which increased in the winter cultivar Isard. The pea NILs are a novel and valuable resource for further understanding the mechanisms underlying QTL and their integration in breeding programs.
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