Evidence map›Paper›PMID 26214684›Full record

Trial reportAIDS (London, England)2015

Shamba Maisha: randomized controlled trial of an agricultural and finance intervention to improve HIV health outcomes.

Sheri D Weiser, Elizabeth A Bukusi, Rachel L Steinfeld, Edward A Frongillo, Elly Weke, Shari L Dworkin, Kyle Pusateri, Stephen Shiboski, Kate Scow, Lisa M Butler and 1 more

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 63 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03741634 nacompletednot on this mapstarted 2018, after this paper: background citation

Shamba Maisha: Assessing the Preliminary Effects of a Multisectoral Agricultural Intervention on the Sexual and Reproductive Health of HIV-affected Adolescent Girls in Western Kenya

TypeinterventionalSponsorUniversity of California, San FranciscoRan2018 to 2019Enrolled241ConditionsAdolescent Behavior, Sexual Behavior, Reproductive BehaviorArmsMulti-sectoral agricultural intervention
NCT06295250 narecruitingnot on this mapstarted 2024, after this paper: background citation

ASHA Bangladesh--An Integrated Intervention to Address Depression in Low Income Rural Women

TypeinterventionalSponsorUniversity of Massachusetts, WorcesterRan2024 to 2026Enrolled600ConditionsDepression, Economic Vulnerability, Anxiety, Culture Specific SymptomsArmsManualized Group Based Psychotherapy, Poverty Alleviation
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  18. Journal of health care for the poor and underserved · 2018
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sheri D WeiseraCenter of Expertise in Women's Health & Empowerment, University of California Global Health Institute bDivision of HIV/AIDS and Center for AIDS Prevention Studies, Departments of Medicine, University of California San Francisco (UCSF) cCentre for Microbiology Research, Kenya Medical Research Institute (KEMRI) dDepartment of Obstetrics, Gynecology & Reproductive Sciences, UCSF eDepartment of Health Promotion, Education and Behavior, University of South Carolina, South Carolina fSocial and Behavioral Sciences gEpidemiology and Biostatistics, UCSF hDepartment of Soil Science and Soil Microbial Biology, University of California Davis iDepartment of Medicine, Division of General Pediatrics, Boston Children's Hospital jDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Elizabeth A Bukusi
Rachel L Steinfeld
Edward A Frongillo
Elly Weke
Shari L Dworkin
Kyle Pusateri
Stephen Shiboski
Kate Scow
Lisa M Butler
Craig R Cohen

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Pilot Agricultural Intervention for Food Security and HIV Outcomes in KenyaR34MH094215 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R, WEISER, SHERI DAWN · 2011 to 2013
$533k
NIAID NIH HHS P30 AI027763NIMH NIH HHS 1R34MH094215NIMH NIH HHS R34 MH094215
6 · The paper itself

Abstract

objectivesFood insecurity and HIV/AIDS outcomes are inextricably linked in sub-Saharan Africa. We report on health and nutritional outcomes of a multisectoral agricultural intervention trial among HIV-infected adults in rural Kenya.

designThis is a pilot cluster randomized controlled trial.

methodsThe intervention included a human-powered water pump, a microfinance loan to purchase farm commodities, and education in sustainable farming practices and financial management. Two health facilities in Nyanza Region, Kenya were randomly assigned as intervention or control. HIV-infected adults 18 to 49 years' old who were on antiretroviral therapy and had access to surface water and land were enrolled beginning in April 2012 and followed quarterly for 1 year. Data were collected on nutritional parameters, CD4 T-lymphocyte counts, and HIV RNA. Differences in fixed-effects regression models were used to test whether patterns in health outcomes differed over time from baseline between the intervention and control arms.

resultsWe enrolled 72 and 68 participants in the intervention and control groups, respectively. At 12 months follow-up, we found a statistically significant increase in CD4 cell counts (165 cells/μl, P < 0.001) and proportion virologically suppressed in the intervention arm compared with the control arm (comparative improvement in proportion of 0.33 suppressed, odds ratio 7.6, 95% confidence interval: 2.2-26.8). Intervention participants experienced significant improvements in food security (3.6 scale points higher, P < 0.001) and frequency of food consumption (9.4 times per week greater frequency, P = 0.013) compared to controls.

conclusionLivelihood interventions may be a promising approach to tackle the intersecting problems of food insecurity, poverty and HIV/AIDS morbidity.

Indexed as

AdolescentAdultAgricultureCD4 Lymphocyte CountFemaleHIV InfectionsHumansKenyaMaleMiddle AgedNutritional StatusRNA, ViralTreatment OutcomeViral LoadYoung AdultRNA, Viral

Identifiers

PMID26214684
PMCPMC4573846

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.