Trial reportPloS one2015
Prevalence and Impact of Sleep Disordered Breathing in Patients with Severe Aortic Stenosis.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Prevalence and Clinical Impact of Obstructive Sleep Apnea in Patients with Severe Aortic Stenosis Undergoing Valve Replacement.Biomedicines · 2025Article
- Multiparametric Outcome Assessment After Transcatheter Aortic Valve Implantation-A Systematic Review.Journal of clinical medicine · 2025Review
- High prevalence of obstructive sleep apnea in a surgical aortic valve replacement cohort: an observational study.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Prevalence of sleep-disordered breathing in patients with mitral regurgitation and the effect of mitral valve repair.Sleep & breathing = Schlaf & Atmung · 2023Article
- Clinical Implications of Changes in Respiratory Instability Following Transcatheter Aortic Valve Replacement.Journal of clinical medicine · 2022Article
- Sleep Quality in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI).International journal of environmental research and public health · 2021Article
- Association Between Sleep Apnea and Valvular Heart Diseases.Frontiers in medicine · 2021Article
- Changes in polysomnographic findings following transcatheter aortic valve implantation in a patient with aortic stenosis.Journal of cardiology cases · 2020Article
- Prevalence, Clinical Profile, and In-Hospital Outcomes of Sleep-Disordered Breathing in Patients Undergoing Transcatheter Aortic Valve Implantation in Japan.Circulation reports · 2019Article
- A clinical approach to obstructive sleep apnea as a risk factor for cardiovascular disease.Vascular health and risk management · 2016Review
- Mental health and transcatheter aortic valve replacement: A scoping systematic review.General hospital psychiatryArticle
- Aortic stenosis and sleep disordered breathing: The effects of interventional management.Science progressReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnlike the well-established association between sleep disordered breathing (SDB) and chronic heart failure, the relationship between SDB and severe aortic stenosis (AS) is not well investigated. Given the increasing prevalence of AS, and the improving prognosis of high risk AS patients attributable to transcatheter aortic valve implantation (TAVI), the prevalence and impact of SDB needs to be better understood. METHODS AND
resultsIn this study, 140 patients with severe AS underwent polygraphy prior to TAVI. Clinical and hemodynamic parameters were recorded. Patients were followed for 573±405 days. We found that 99/140 patients (71%) had SDB with a mean apnoea-hypopnoea-index of 24±17/h. SDB was mild in 27%, moderate in 23% and severe in 21% of patients. In addition, 35 patients (25%) had obstructive sleep apnoea (OSA), whereas 64 patients (46%) had central sleep apnoea (CSA). Patients with OSA had predominantly mild SDB (20/38 pts.), and patients with CSA mostly had severe SDB (24/29 pts.). The prevalence and distribution of OSA and CSA were independent of left ventricular function. Overall, 1 and 2 year survival rates (74% and 71%, resp.) did not differ significantly between patients without SDB or those with OSA and CSA (p=0.81).
conclusionsSDB, with a preponderance of CSA, was found to be highly prevalent in patients with high-grade AS scheduled for TAVI. SDB prevalence was independent of left ventricular function. Mortality after TAVI was not influenced by the type or severity of SDB.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.