ReviewDrugs in context2015
A review of current treatment strategies for gestational diabetes mellitus.
Review in Drugs in context, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis.PLoS medicine · 2019Pooled it
- Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews.The Cochrane database of systematic reviews · 2018Pooled it
- Telemedicine Technologies for Diabetes in Pregnancy: A Systematic Review and Meta-Analysis.Journal of medical Internet research · 2016Pooled it
- Nanoliposome-based drug delivery systems for the treatment of diabetes mellitus: a review.RSC advances · 2025Review
- Article
- Diet intake and adherence to recommendations in women with gestational diabetes mellitus.European journal of clinical nutrition · 2025Article
- Beyond one size fits all: Probing patient choices in gestational diabetes management, from screening to postpartum.Chronic diseases and translational medicine · 2025Review
- Loss of RIP3 alleviates insulin resistance and inflammation in gestational diabetes mellitus mice via TLR4/MyD88/NF-κB signaling pathway.BMC pregnancy and childbirth · 2025Article
- Implementing telemedicine for the care of women with gestational diabetes mellitus in a rural hospital: an observational retrospective study.BMC health services research · 2024Observational
- Metformin Impacts Human Syncytiotrophoblast Mitochondrial Function from Pregnancies Complicated by Obesity and Gestational Diabetes Mellitus in a Sexually Dimorphic Manner.Antioxidants (Basel, Switzerland) · 2023Article
- Gut Microbiota Associated with Gestational Health Conditions in a Sample of Mexican Women.Nutrients · 2022Article
- Predictors of metformin monotherapy failure in gestational diabetes mellitus.Endocrine connections · 2022Article
- Comparison of neonatal and maternal outcomes of anti-diabetic drugs in the treatment of gestational diabetes mellitus: Findings from Bayesian network meta-analysis.Journal of family medicine and primary care · 2022Review
- Bioenergetics adaptations and redox homeostasis in pregnancy and related disorders.Molecular and cellular biochemistry · 2021Review
- Perinatal outcomes in twin pregnancies complicated by gestational diabetes.American journal of obstetrics & gynecology MFM · 2021Article
- A Glimpse at the Size of the Fetal Liver-Is It Connected with the Evolution of Gestational Diabetes?International journal of molecular sciences · 2021Review
- Interaction between Metformin, Folate and Vitamin BInternational journal of molecular sciences · 2021Review
- Characterization of women with gestational diabetes who failed to achieve glycemic control by lifestyle modifications.Archives of gynecology and obstetrics · 2021Article
- Adherence to Antidiabetic Medications among Women with Gestational Diabetes.Journal of diabetes research · 2021Review
- Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells.Pharmaceuticals (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Approximately 90% of diabetes cases in pregnant women are considered gestational diabetes mellitus (GDM). It is well known that uncontrolled glucose results in poor pregnancy outcomes in both the mother and fetus. Worldwide there are many guidelines with recommendations for appropriate management strategies for GDM once lifestyle modifications have been instituted and failed to achieve control. The efficacy and particularly the safety of other treatment modalities for GDM has been the source of much debate in recent years. Studies that have demonstrated the safety and efficacy of both glyburide and metformin in the management of patients with GDM will be reviewed. There is a lack of evidence with other oral and injectable non-insulin agents to control blood glucose in GDM. The role of insulin will be discussed, with emphasis on insulin analogs. Ideal patient characteristics for each treatment modality will be reviewed. In addition, recommendations for postpartum screening of patients will be described as well as recommendations for use of agents to manage subsequent type 2 diabetes in patients who are breastfeeding.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.