ArticleKorean journal of pediatrics2015
Thyroid dysfunction in very low birth weight preterm infants.
Article in Korean journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 50 citations in OpenAlex.
- Thyroid function tests in healthy kittens aged between 2 and 16 weeks.Journal of feline medicine and surgery · 2024Article
- Hypothyroidism in Patients with Down Syndrome: Prevalence and Association with Congenital Heart Defects.Children (Basel, Switzerland) · 2024Article
- Development of delayed thyroid stimulating hormone elevation in small-for-gestational-age infants: is a second screening needed?Annals of pediatric endocrinology & metabolism · 2023Article
- Article
- A suggested screening method for hypothyroidism in very preterm and/or very low birth weight neonates.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2022Article
- Targeted Secondary Screening for Congenital Hypothyroidism in High-Risk Neonates: A 9 Year Review in a Large California Health Care System.International journal of neonatal screening · 2021Article
- Article
- [A clinical analysis of hypothyroidism in very low birth weight/extremely low birth weight infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Thyroxine Threshold Is Linked to Impaired Outcomes in Preterm Infants.Frontiers in pediatrics · 2020Article
- Thyroid dysfunction in preterm infants born before 32 gestational weeks.BMC pediatrics · 2019Article
- Congenital Hypothyroidism in Preterm Newborns: A Retrospective Study Arising from a Screening Program in Fars Province, Southwestern Iran.Oman medical journal · 2019Article
- Screening and management of thyroid dysfunction in preterm infants.Annals of pediatric endocrinology & metabolism · 2019Article
- Article
- Antenatal steroids and thyroid hormone function in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2018Article
- Neonatal screening in the Czech Republic: increased prevalence of selected diseases in low birthweight neonates.European journal of pediatrics · 2018Article
- Clinical course of infants with congenital heart disease who developed thyroid dysfunction within 100 days.Annals of pediatric endocrinology & metabolism · 2017Article
- Congenital hypothyroidism with delayed thyroid-stimulating hormone elevation in premature infants born at less than 30 weeks gestation.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThyroid dysfunction is common in preterm infants. Congenital hypothyroidism causes neurodevelopmental impairment, which is preventable if properly treated. This study was conducted to describe the characteristics of thyroid dysfunction in very low birth weight infants (VLBWIs), evaluate risk factors of hypothyroidism, and suggest the reassessment of thyroid function with an initially normal thyroid-stimulating hormone (TSH) as part of a newborn screening test.
methodsVLBWIs (January 2010 to December 2012) were divided into two groups according to dysfunction-specific thyroid hormone replacement therapy, and associated factors were evaluated.
resultsOf VLBWIs, 246 survivors were enrolled. Only 12.2% (30/246) of enrolled subjects exhibited thyroid dysfunction requiring thyroid hormone replacement. Moreover, only one out of 30 subjects who required thyroid hormone treatment had abnormal thyroid function in the newborn screening test with measured TSH. Most of the subjects in the treatment group (22/30) exhibited delayed TSH elevation. Gestational age, Apgar score, antenatal steroids therapy, respiratory distress syndrome, patent ductus arteriosus, sepsis, intraventricular hemorrhage, postnatal steroids therapy, and duration of mechanical ventilation did not differ between the two groups. Birth weight was smaller and infants with small for gestational age were more frequent in the treatment group.
conclusionPhysicians should not rule out suggested hypothyroidism, even when thyroid function of a newborn screening test is normal. We suggest retesting TSH and free thyroxine in high risk preterm infants with an initially normal TSH level using a newborn screening test.
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