Evidence map›Paper›PMID 26213406›Full record

ArticleProgress in community health partnerships : research, education, and action2015

Considering the Role of Stress in Populations of High-Risk, Underserved Community Networks Program Centers.

James R Hébert, Kathryn L Braun, Joseph Keawe'aimoku Kaholokula, Cheryl A Armstead, James B Burch, Beti Thompson

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Progress in community health partnerships : research, education, and action, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03975439 (Chronic Kidney Disease and Cardiovascular Disease Risk Assessment in Yakima County), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03975439 withdrawnnot on this mapstarted 2020, after this paper: background citation

Chronic Kidney Disease and Cardiovascular Disease Risk Assessment in Yakima County

TypeobservationalSponsorPacific Northwest University of Health SciencesRan2020 to 2020Enrolled0ConditionsChronic Kidney Diseases, Diabetes Mellitus, HypertensionArmsHemoglobin A1C, Urinalysis, Whole blood creatinine level
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

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  8. Focus on disability-free life expectancy: implications for health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
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  11. Understanding Racial Disparities in Gastrointestinal Cancer Outcomes: Lack of Surgery Contributes to Lower Survival in African American Patients.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  12. Early-onset colorectal cancer: initial clues and current views.Nature reviews. Gastroenterology & hepatology · 2020
    Review
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  17. A Legacy of Science and Community Engagement via the Community Networks Program.Progress in community health partnerships : research, education, and action · 2015
    Article
  18. Community-Based Participatory Research Adds Value to the National Cancer Institute's Research Portfolio.Progress in community health partnerships : research, education, and action · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

James R Hébert
Kathryn L Braun
Joseph Keawe'aimoku Kaholokula
Cheryl A Armstead
James B Burch
Beti Thompson
University of South Carolina · USFred Hutch Cancer Center · USPancreatic Cancer Action Network · USPapa Ola Lokahi · USUniversity of Hawaiʻi at Mānoa · US

Funding

RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
Training ProgramU54CA153461 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HEBERT, JAMES R · 2010 to 2015
$4.8M
Training ProgramU54CA153502 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMPSON, BETI · 2010 to 2015
$4.7M
Training ProgramU54CA153459 · NCI · PAPA OLA LOKAHI · PI BRAUN, KATHRYN LENZNER · 2010 to 2015
$4.5M
Expanding Mentoring Capacity in High-Risk PopulationsK05CA136975 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HEBERT, JAMES R · 2009 to 2013
$801k
NCI NIH HHS K05 CA136975NCI NIH HHS U54 CA153459NCI NIH HHS U54 CA153461NCI NIH HHS U54 CA153502NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

backgroundCancer disparities are associated with a broad range of sociocultural determinants of health that operate in community contexts. High-risk populations may be more vulnerable to social and environmental factors that lead to chronic stress. Theoretical and empirical research indicates that exposure to contextual and sociocultural stress alters biological systems, thereby influencing cancer risk, progression, and, ultimately, mortality.

objectiveWe sought to describe contextual pathways through which stress likely increases cancer risk in high-risk, underserved populations.

methodsThis review presents a description of the link between contextual stressors and disease risk disparities within underserved communities, with a focus on 1) stress as a proximal link between biological processes, such as cytokine responses, inflammation, and cancer and 2) stress as a distal link to cancer through biobehavioral risk factors such as poor diet, physical inactivity, circadian rhythm or sleep disruption, and substance abuse. These concepts are illustrated through application to populations served by three National Cancer Institute-funded Community Networks Program Centers (CNPCs): African Americans in the Deep South (the South Carolina Cancer Disparities Community Network [SCCDCN]), Native Hawaiians ('Imi Hale-Native Hawaiian Cancer Network), and Latinos in the Lower Yakima Valley of Washington State (The Center for Hispanic Health Promotion: Reducing Cancer Disparities).

conclusionsStress experienced by the underserved communities represented in the CNPCs is marked by social, biological, and behavioral pathways that increase cancer risk. A case is presented to increase research on sociocultural determinants of health, stress, and cancer risk among racial/ethnic minorities in underserved communities.

Indexed as

Health Status DisparitiesCommunity-Based Participatory ResearchCommunity NetworksCultureHealth BehaviorHumansMinority GroupsNational Cancer Institute (U.S.)NeoplasmsRacial GroupsStress, PsychologicalUnited States

Identifiers

PMID26213406
PMCPMC4702949
OpenAlexW961430681

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.