ArticleCurrent biology : CB2015
Morphogenesis of the Fission Yeast Cell through Cell Wall Expansion.
Article in Current biology : CB, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- A surface morphology-based inference method for the cell wall elasticity profile in tip-growing cells.PLoS computational biology · 2026Article
- Frog-killing chytrid fungus deploys different strategies to regulate intracellular pressure in developmental states that have or lack a cell wall.Current biology : CB · 2025Article
- Article
- Article
- The curtain model as an alternative and complementary to the classic turgor concept of filamentous fungi.Archives of microbiology · 2025Review
- Analysis of Cell Wall Mechanics in Fission Yeast.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Mechanical strategies supporting growth and size diversity in Filamentous Fungi.Molecular biology of the cell · 2024Article
- Processes Controlling the Contractile Ring during Cytokinesis in Fission Yeast, Including the Role of ESCRT Proteins.Journal of fungi (Basel, Switzerland) · 2024Review
- Quantifying turgor pressure in budding and fission yeasts based upon osmotic properties.Molecular biology of the cell · 2023Article
- Quantifying turgor pressure in budding and fission yeasts based upon osmotic properties.bioRxiv : the preprint server for biology · 2023Article
- Elevated levels of sphingolipid MIPC in the plasma membrane disrupt the coordination of cell growth with cell wall formation in fission yeast.PLoS genetics · 2023Article
- Activation of CWI pathway through high hydrostatic pressure, enhancing glycerol efflux via the aquaglyceroporin Fps1 inMolecular biology of the cell · 2023Article
- Cell wall dynamics stabilize tip growth in a filamentous fungus.PLoS biology · 2023Article
- Control of nuclear size by osmotic forces ineLife · 2022Article
- Laser ablation reveals the impact of Cdc15p on the stiffness of the contractile ring.Molecular biology of the cell · 2022Article
- Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization.Developmental cell · 2022Article
- Fission yeast polycystin Pkd2p promotes cell size expansion and antagonizes the Hippo-related SIN pathway.Journal of cell science · 2022Article
- Characterizing non-exponential growth and bimodal cell size distributions in fission yeast: An analytical approach.PLoS computational biology · 2022Article
- Ultrastructural plasma membrane asymmetries in tension and curvature promote yeast cell fusion.The Journal of cell biology · 2021Article
- Sequestration of the exocytic SNARE Psy1 into multiprotein nodes reinforces polarized morphogenesis in fission yeast.Molecular biology of the cell · 2021Article
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4 authors.
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Abstract
The shape of walled cells such as fungi, bacteria, and plants are determined by the cell wall. Models for cell morphogenesis postulate that the effects of turgor pressure and mechanical properties of the cell wall can explain the shapes of these diverse cell types. However, in general, these models await validation through quantitative experiments. Fission yeast Schizosaccharomyces pombe are rod-shaped cells that grow by tip extension and then divide medially through formation of a cell wall septum. Upon cell separation after cytokinesis, the new cell ends adopt a rounded morphology. Here, we show that this shape is generated by a very simple mechanical-based mechanism in which turgor pressure inflates the elastic cell wall in the absence of cell growth. This process is independent of actin and new cell wall synthesis. To model this morphological change, we first estimate the mechanical properties of the cell wall using several approaches. The lateral cell wall behaves as an isotropic elastic material with a Young's modulus of 50 ± 10 MPa inflated by a turgor pressure estimated to be 1.5 ± 0.2 MPa. Based upon these parameters, we develop a quantitative mechanical-based model for new end formation that reveals that the cell wall at the new end expands into its characteristic rounded shape in part because it is softer than the mature lateral wall. These studies provide a simple example of how turgor pressure expands the elastic cell wall to generate a particular cell shape.
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