Evidence map›Paper›PMID 26212619›Full record

ReviewThe American journal of case reports2015

Primary Malignant Melanoma of the Esophagus: A Case Report and Review of the Literature.

Antonio Navarro-Ballester, Susana De Lazaro-De Molina, John Gaona-Morales

Abstract readCase ReportsReview
In one paragraph

Review in The American journal of case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Unveiling a Rare Cause of Dysphagia.GE Portuguese journal of gastroenterology · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Primary Esophageal Malignant Melanoma in Korea: Clinical features, Management and Prognosis.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Antonio Navarro-BallesterDepartment of Diagnostic and Therapeutic Radiology, Hospital General Universitario de Castellón, Castellón de la Plana, Spain.
Susana De Lazaro-De MolinaDepartment of Diagnostic and Therapeutic Radiology, Hospital General Universitario de Castellón, Castellón de la Plana, Spain.
John Gaona-MoralesDepartment of Pathology, Hospital General Universitario de Castellón, Castellón de la Plana, Spain.
Hospital General Universitari de Castelló · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Primary malignant melanoma of the esophagus (PMME) is a rare cancer with a poor prognosis. It is often difficult to differentiate from non-epithelial malignant tumors, and immunohistochemical staining may be needed to diagnose the condition. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The average survival rate after surgery is 34.5 months. At the time of diagnosis, 40-80% of cases have local regional lymph node metastases. CASE REPORT The case of a 67-year-old male patient with PMME is reported. He presented with progressive dysphagia. A computerized tomography was performed in which a polypoid mass was observed in the distal esophagus. It was originally suspected to be an adenocarcinoma, but was subsequently correctly diagnosed by immunohistochemical staining with HMB-45 antibody and by the presence of S-100 protein. A subtotal esophagectomy was performed. CONCLUSIONS Very few cases of PMME have been reported in the literature and there is only limited clinical experience with this disease. Therefore, it is very difficult to establish clear criteria for clinical recognition of this type of melanoma. Early histopathological confirmation of the character is essential for further treatment in case of confirmation of malignancy.

Indexed as

AgedEsophageal NeoplasmsHumansMaleMelanoma

Identifiers

PMID26212619
PMCPMC4520419
OpenAlexW1784830037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.