Evidence map›Paper›PMID 26212401›Full record

Observational studyArchives of physical medicine and rehabilitation2015

Enteral Nutrition for Patients With Traumatic Brain Injury in the Rehabilitation Setting: Associations With Patient Preinjury and Injury Characteristics and Outcomes.

Susan D Horn, Merin Kinikini, Linda W Moore, Flora M Hammond, Murray E Brandstater, Randall J Smout, Ryan S Barrett

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in Archives of physical medicine and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. CORRELATION BETWEEN TRAUMATIC BRAIN INJURY, OBESITY AND INSULIN-RESISTANCE - A CASE REPORT.Journal of rehabilitation medicine. Clinical communications · 2025
    Article
  4. Article
  5. Determination of calorie and protein intake among acute and sub-acute traumatic brain injury patients.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2020
    Observational
  6. Article
  7. Practice Guidelines for Nutrition in Critically Ill Patients: A Relook for Indian Scenario.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018
    Article
  8. Research Design Options for Intervention Studies.Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association · 2017
    Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Susan D HornInstitute for Clinical Outcomes Research, International Severity Information Systems, Inc, Salt Lake City, UT. Electronic address: susan.horn@hsc.utah.edu.
Merin KinikiniNeuro Specialty Rehabilitation Unit, Intermountain Medical Center, Salt Lake City, UT.
Linda W MooreHouston Methodist Hospital, Houston, TX.
Flora M HammondCarolinas Rehabilitation, Charlotte, NC; Indiana University, Indianapolis, IN.
Murray E BrandstaterLoma Linda University Medical Center, Loma Linda, CA.
Randall J SmoutInstitute for Clinical Outcomes Research, International Severity Information Systems, Inc, Salt Lake City, UT.
Ryan S BarrettInstitute for Clinical Outcomes Research, International Severity Information Systems, Inc, Salt Lake City, UT.
International Severity Information Systems (United States) · USHouston Methodist · USIntermountain Medical Center · USLoma Linda University Medical Center · USUniversity of North Carolina at Charlotte · US

Funding

Improving Outcomes in Acute Rehabilitation for TBIR01HD050439 · NICHD · INTERNATIONAL SEVERITY INFO SYSTEMS,INC. · PI HORN, SUSAN D · 2007 to 2011
$3.3M
NICHD NIH HHS 1R01HD050439-01NICHD NIH HHS R01 HD050439
6 · The paper itself

Abstract

objectiveTo determine the association of enteral nutrition (EN) with patient preinjury and injury characteristics and outcomes for patients receiving inpatient rehabilitation after traumatic brain injury (TBI).

designProspective observational study.

settingNine rehabilitation centers.

participantsPatients (N=1701) admitted for first full inpatient rehabilitation after TBI.

interventionsNot applicable.

main outcome measuresFIM at rehabilitation discharge, length of stay, weight loss, and various infections.

resultsThere were many significant differences in preinjury and injury characteristics between patients who received EN and patients who did not. After matching patients with a propensity score of >40% for the likely use of EN, patients receiving EN with either a standard or a high-protein formula (>20% of calories coming from protein) for >25% of their rehabilitation stay had higher FIM motor and cognitive scores at rehabilitation discharge and less weight loss than did patients with similar characteristics not receiving EN.

conclusionsFor patients receiving inpatient rehabilitation after TBI and matched on a propensity score of >40% for the likely use of EN, clinicians should strongly consider, when possible, EN for ≥25% of the rehabilitation stay and especially with a formula that contains at least 20% protein rather than a standard formula.

Indexed as

AdultBrain InjuriesEnteral NutritionFemaleHumansInjury Severity ScoreInpatientsLength of StayMaleMiddle AgedProspective StudiesRecovery of FunctionRegression AnalysisRehabilitation CentersTreatment OutcomeBrain injuriesComparative effectiveness researchEnteral nutritionPropensity scoreRehabilitation

Identifiers

PMID26212401
PMCPMC4545614
OpenAlexW1604665358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.