Trial reportArthritis care & research2016
Rest Pain and Movement-Evoked Pain as Unique Constructs in Hip and Knee Replacements.
Trial report in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Pooled it
- Pooled it
- Post-operative patient-related risk factors for chronic pain after total knee replacement: a systematic review.BMJ open · 2017Pooled it
- Trial
- Rethinking measurement of movement-evoked pain with digital technology.The journal of pain · 2026Article
- Is There a Difference in Factors Affecting Rest Pain and Pain Intensity during Movement at 1 Year Post-total Knee Arthroplasty?Physical therapy research · 2026Article
- Exploring the interplay between pain processing mechanisms, psychosocial factors, and functional outcomes in patients with chronic low back pain: an exploratory study.Annals of medicine · 2025Article
- Rethinking Measurement of Movement-Evoked Pain with Digital Technology.medRxiv : the preprint server for health sciences · 2025Article
- "Pain Prehabilitation" in Major Joint Surgery: The Way Forward to Improve Outcomes and Prevent Pain Chronicity.Journal of clinical medicine · 2025Review
- The Role of Health Psychology in Surgical Prehabilitation: Insights From REST, a Preoperative Sleep Intervention for Total Knee Replacement Patients.Musculoskeletal care · 2025Article
- Research on the Developmental Trajectory of Movement-Evoked Pain and Its Potential Predictors in Patients After Knee Arthroplasty.Journal of pain research · 2025Article
- The Impact of Acute Postoperative Pain in Developing Chronic Pain after Total Knee Arthroplasty.Neurology international · 2024Article
- Phenotypes of osteoarthritis-related knee pain and their transition over time: data from the osteoarthritis initiative.BMC musculoskeletal disorders · 2024Article
- Pain Catastrophizing and Acute Post-Surgical Pain in Knee Arthroplasty Patients: The Moderating Role of Social Support.Journal of pain research · 2024Article
- Efficacy of erector spine plane block in two different approaches to lumbar spinal fusion surgery: a retrospective pilot study.Frontiers in medicine · 2024Article
- Factors associated with persistent postsurgical pain after total knee or hip joint replacement: a systematic review and meta-analysis.Pain reports · 2023Review
- Prevalence and Predictors of Chronic Pain with Two-Year Follow-Up After Knee Arthroplasty.Journal of pain research · 2022Article
- The duration of postoperative analgesic use after total knee arthroplasty and nomogram for predicting prolonged analgesic use.Frontiers in surgery · 2022Article
- Activity-related pain predicts pain and functional outcomes in people with knee osteoarthritis: A longitudinal study.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Early post-immobilization pain at rest, movement evoked pain, and their ratio as potential predictors of pain and disability at six- and 12-months after distal radius fracture.Archives of physiotherapy · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThere is limited information about the extent to which the association between preoperative and chronic postoperative pain is mediated via pain-on-movement or pain-at-rest. We explored these associations in patients undergoing total hip replacement (THR) and total knee replacement (TKR).
methodsA total of 322 and 316 patients receiving THR and TKR, respectively, were recruited into a single-center UK cohort (Arthroplasty Pain Experience) study. Preoperative, acute postoperative, and 12-month pain severity was measured using self-reported pain instruments. The association between preoperative/acute pain and chronic postoperative pain was investigated using structural equation modeling (SEM).
resultsPatients with high levels of preoperative pain were more likely to report chronic pain after THR (β = 0.195, P = 0.02) and TKR (β = 0.749, P < 0.0001). Acute postoperative pain-on-movement was not associated with chronic pain after TKR or THR after adjusting for preoperative pain; however, acute pain-at-rest was associated with chronic pain after THR (β = 0.20, P < 0.0002) but not TKR after adjusting for preoperative pain. Analysis of pain-at-rest and pain-on-movement highlighted differences between THR and TKR patients. Chronic pain-at-rest after THR was weakly associated with pain-at-rest during the preoperative (β = 0.11, P = 0.068) and acute postoperative period (β = 0.21, P < 0.0001). In contrast, chronic pain-on-movement after TKR was strongly associated with the severity of pain-on-movement during the preoperative period (β = 0.51, P = 0.001).
conclusionSEM illustrated the different patterns of association between measures of pain over time in patients undergoing THR and TKR for osteoarthritis. These findings highlight the importance of future work that explores the mechanisms underlying pain-on-movement and pain-at-rest.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.