Evidence map›Paper›PMID 26212205›Full record

ReviewBiosensors & bioelectronics2016

Glyconanomaterials for biosensing applications.

Nanjing Hao, Kitjanit Neranon, Olof Ramström, Mingdi Yan

Abstract readReview
In one paragraph

Review in Biosensors & bioelectronics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Carbohydrate-based biosensors for enhanced pathogen detection.Analytical and bioanalytical chemistry · 2026
    Review
  2. Green synthesis of glyco-CuInSJournal of nanobiotechnology · 2023
    Article
  3. Article
  4. Article
  5. From structure to function - Ligand recognition by myeloid C-type lectin receptors.Computational and structural biotechnology journal · 2022
    Review
  6. Article
  7. Review
  8. Quantification of binding affinity of glyconanomaterials with lectins.Chemical communications (Cambridge, England) · 2020
    Review
  9. Glycan Nanobiosensors.Nanomaterials (Basel, Switzerland) · 2020
    Review
  10. Review
  11. Article
  12. Review
  13. Biomimetic hierarchical walnut kernel-like and erythrocyte-like mesoporous silica nanomaterials: controllable synthesis and versatile applications.Microporous and mesoporous materials : the official journal of the International Zeolite Association · 2018
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nanjing HaoDepartment of Chemistry, University of Massachusetts Lowell, 1 University Avenue, Lowell, MA 01854, USA.
Kitjanit NeranonDepartment of Chemistry, KTH-Royal Institute of Technology, Teknikringen 30, S-10044 Stockholm, Sweden.
Olof RamströmDepartment of Chemistry, KTH-Royal Institute of Technology, Teknikringen 30, S-10044 Stockholm, Sweden. Electronic address: ramstrom@kth.se.
Mingdi YanDepartment of Chemistry, University of Massachusetts Lowell, 1 University Avenue, Lowell, MA 01854, USA; Department of Chemistry, KTH-Royal Institute of Technology, Teknikringen 30, S-10044 Stockholm, Sweden. Electronic address: mingdi_yan@uml.edu.

Funding

Photogenerated Carbohydrate MicroarraysR01GM080295 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2008 to 2012
$2.0M
Maltoheptaose based nanotherapeutics for multidrug resistant bacterial infectionR21AI109896 · NIAID · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2014 to 2015
$444k
NIAID NIH HHS R21 AI109896NIAID NIH HHS R21AI109896NIGMS NIH HHS R01 GM080295NIGMS NIH HHS R01GM080295
6 · The paper itself

Abstract

Nanomaterials constitute a class of structures that have unique physiochemical properties and are excellent scaffolds for presenting carbohydrates, important biomolecules that mediate a wide variety of important biological events. The fabrication of carbohydrate-presenting nanomaterials, glyconanomaterials, is of high interest and utility, combining the features of nanoscale objects with biomolecular recognition. The structures can also produce strong multivalent effects, where the nanomaterial scaffold greatly enhances the relatively weak affinities of single carbohydrate ligands to the corresponding receptors, and effectively amplifies the carbohydrate-mediated interactions. Glyconanomaterials are thus an appealing platform for biosensing applications. In this review, we discuss the chemistry for conjugation of carbohydrates to nanomaterials, summarize strategies, and tabulate examples of applying glyconanomaterials in in vitro and in vivo sensing applications of proteins, microbes, and cells. The limitations and future perspectives of these emerging glyconanomaterials sensing systems are furthermore discussed.

Indexed as

NanotechnologyBacteriaBiosensing TechniquesCarbohydratesCell TrackingLigandsNanoparticlesNanostructuresProteinsCarbohydratesLigandsProteinsBiosensingCarbohydratesGlyconanomaterialsGlycoscienceNanotechnology

Identifiers

PMID26212205
PMCPMC4637221

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.