Evidence map›Paper›PMID 26211415›Full record

Trial reportAging & mental health2016

A pilot randomized controlled trial of mindfulness-based stress reduction for caregivers of family members with dementia.

Kirk Warren Brown, Constance L Coogle, Jacob Wegelin

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Aging & mental health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03354819 (Effects of a Modified Mindfulness-based Cognitive Therapy for Family Caregivers of People With Dementia in Stress Reduction), which is not on this map. Cited by 50 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03354819 nacompletednot on this mapstarted 2017, after this paper: background citation

Effects of a Modified Mindfulness-based Cognitive Therapy for Family Caregivers of People With Dementia in Stress Reduction: A Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2017 to 2019Enrolled113ConditionsCarer Stress Syndrome, DementiaArmsModified MBCT, SIRE on dementia
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Mindfulness-Based Programmes for Work Performance: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Stress and health : journal of the International Society for the Investigation of Stress · 2025
    Pooled it
  2. Resilience Interventions Conducted in Western and Eastern Countries-A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  17. Mindfulness-Based Mobile Application for African American Caregivers.Journal of technology in behavioral science · 2024
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kirk Warren Browna Department of Psychology , Virginia Commonwealth University , Richmond , VA , USA.
Constance L Coogleb Virginia Center on Aging , Virginia Commonwealth University , Richmond , VA , USA.
Jacob Wegelinc Department of Biostatistics , Virginia Commonwealth University Medical Center , Richmond , VA , USA.

Funding

Center for Clinical and Translational ResearchUL1TR000058 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2015
$12.5M
NCATS NIH HHS UL1 TR000058
6 · The paper itself

Abstract

objectivesThe majority of care for those with Alzheimer's disease and other age-related dementias is provided in the home by family members. To date, there is no consistently effective intervention for reducing the significant stress burden of many family caregivers. The present pilot randomized controlled trial tested the efficacy of an adapted, eight-week mindfulness-based stress reduction (MBSR) program, relative to a near structurally equivalent, standard social support (SS) control condition for reducing caregiver stress and enhancing the care giver-recipient relationship.

methodThirty-eight family caregivers were randomized to MBSR or SS, with measures of diurnal salivary cortisol, and perceived stress, mental health, experiential avoidance, caregiver burden, and relationship quality collected pre- and post-intervention and at three-month follow-up.

resultsMBSR participants reported significantly lower levels of perceived stress and mood disturbance at post-intervention relative to SS participants. At three-month follow-up, participants in both treatment conditions reported improvements on several psychosocial outcomes. At follow-up, there were no condition differences on these outcomes, nor did MBSR and SS participants differ in diurnal cortisol response change over the course of the study.

conclusionBoth MBSR and SS showed stress reduction effects, and MBSR showed no sustained neuroendocrine and psychosocial advantages over SS. The lack of treatment condition differences could be attributable to active ingredients in both interventions, and to population-specific and design factors.

Indexed as

DementiaFamilyMindfulnessAdultAgedAged, 80 and overCaregiversFemaleHumansHydrocortisoneMaleMiddle AgedPilot ProjectsSalivaSelf ReportSocial SupportHydrocortisonemindfulness-based stress reductionsalivary cortisolsocial supportstress

Identifiers

PMID26211415
PMCPMC5070659

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.