Evidence map›Paper›PMID 26210519›Full record

ArticleJournal of autism and developmental disorders2016

Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis.

I Carina Gillberg, Adam Helles, Eva Billstedt, Christopher Gillberg

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Traumatic Experiences, Psychological Distress and Suicide-Related Behaviors in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  6. Association Between Autism and PTSD Among Adult Psychiatric Outpatients.Journal of autism and developmental disorders · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Prevalence of Autism Spectrum Disorders in Adult Outpatient Psychiatry.Journal of autism and developmental disorders · 2022
    Article
  19. Article
  20. Adults with Autism: Changes in Understanding Since DSM-111.Journal of autism and developmental disorders · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

I Carina GillbergGillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, University of Gothenburg, Kungsgatan 12, 411 19, Gothenburg, Sweden.
Adam HellesGillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, University of Gothenburg, Kungsgatan 12, 411 19, Gothenburg, Sweden. adam.helles@gnc.gu.se.
Eva BillstedtGillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, University of Gothenburg, Kungsgatan 12, 411 19, Gothenburg, Sweden.
Christopher GillbergGillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, University of Gothenburg, Kungsgatan 12, 411 19, Gothenburg, Sweden.
University of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13-26 years). Only three of the 50 men had never met criteria for an additional psychiatric/neurodevelopmental diagnosis and more than half had ongoing comorbidity (most commonly either ADHD or depression or both). Any psychiatric comorbidity increased the risk of poorer outcome. The minority of the AS group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity. The high rate of psychiatric/neurodevelopmental comorbidities underscores the need for a full psychiatric/neurodevelopmental assessment at follow-up of males with AS.

Indexed as

AdolescentAdultAsperger SyndromeChildCohort StudiesComorbidityDepressionDepressive DisorderHumansMaleMental DisordersNeurodevelopmental DisordersProspective StudiesADHDAsperger syndromeAutism spectrum disorderDCDDepressionLong-term follow-upNeurodevelopmentalPsychiatric disorderSchizophrenia

Identifiers

PMID26210519
OpenAlexW1934558299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.