Evidence map›Paper›PMID 26210489›Full record

ArticleLipids2015

Natural Rumen-Derived trans Fatty Acids Are Associated with Metabolic Markers of Cardiac Health.

Marine S Da Silva, Pierre Julien, Louis Pérusse, Marie-Claude Vohl, Iwona Rudkowska

Abstract read
PubMed Publisher
In one paragraph

Article in Lipids, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
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  8. Article
  9. Review
  10. Differential Effects of Ruminant and Industrial 18-CarbonMolecules (Basel, Switzerland) · 2021
    Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Marine S Da SilvaEndocrinology and Nephrology, T-4-55B, CHU de Québec Research Center, CHUL-2705, boul. Laurier, Québec, QC, G1V 4G2, Canada.
Pierre Julien
Louis Pérusse
Marie-Claude Vohl
Iwona Rudkowska
Université Laval · CAWeatherford College · US

Funding

Canadian Institutes of Health Research MOP-200609Canadian Institutes of Health Research OHN 63276
6 · The paper itself

Abstract

Evidence suggests that industrial trans fatty acids (iTFA) impair lipid profiles while ruminant trans fatty acids (rTFA) may lower insulin resistance and blood pressure. The objective of this article was to determine if the plasma phospholipid percentage of rTFA is associated with a favorable cardiometabolic profile. We collected fasting blood samples from 200 individuals from Quebec city (QC, Canada) aged from 18 to 55 years old, including 100 obese (BMI ≥ 30 kg m(-2)) and 100 non-obese (BMI < 30 kg m(-2)) men and women. Fatty acid levels in plasma phospholipids were determined using gas chromatography. After separating the subjects into two groups, according to the median percentage of rTFA in plasma phospholipids, participants in the group with higher percentages of rTFA (0.86 ± 0.24 %) had higher adiponectin levels (p = 0.01) and a lower blood pressure (systolic, p = 0.005; diastolic, p = 0.04). In contrast, concentrations in plasma phospholipids of elaidic acid, a major iTFA, are positively correlated with glycemia in non-obese subjects (p = 0.01) and with both triacylglycerol (TAG) (p = 0.0007) and total cholesterol (TC) (p = 0.009) in obese subjects. These data suggest that rTFA may have beneficial effects on cardiometabolic risk factors conversely to their counterpart iTFA. Dietary sources of TFA should be taken into account in future cardiometabolic studies.

Indexed as

AdiposityAdolescentAdultAnimalsBiomarkersBlood PressureCanadaCardiovascular DiseasesDairy ProductsDietary FatsFemaleHumansLipid MetabolismMaleMeatMiddle AgedBiomarkersDietary Fatselaidic acidOleic AcidOleic AcidsTrans Fatty Acids

Identifiers

PMID26210489
OpenAlexW1005656837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.