Evidence map›Paper›PMID 26210474›Full record

Observational studyLung2015

Where is Noninvasive Ventilation Actually Delivered for Acute Respiratory Failure?

Aylin Ozsancak Ugurlu, Samy S Sidhom, Ali Khodabandeh, Michael Ieong, Chester Mohr, Denis Y Lin, Irwin Buchwald, Imad Bahhady, John Wengryn, Vinay Maheshwari and 1 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Lung, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 3 countries.

Aylin Ozsancak UgurluDepartment of Pulmonary Disease, Baskent University, Oymaci sok. No: 2, 34662, Altunizade/Istanbul, Turkey. aozsancak@hotmail.com.
Samy S SidhomPulmonary Department, Newton-Wellesley Hospital, Newton, MA, USA.
Ali KhodabandehMass Lung and Allergy PC, Leominster, MA, USA.
Michael IeongBoston Medical Center, Boston, MA, USA.
Chester MohrCape Cod Health Systems, Hyannis, MA, USA.
Denis Y LinLowell General Hospital, Lowell, MA, USA.
Irwin BuchwaldSaints Medical Center, Lowell, MA, USA.
Imad BahhadyMorton Hospital, Taunton, MA, USA.
John WengrynJordan Hospital, Plymouth, MA, USA.
Vinay MaheshwariPulmonary Associates, Newark, DE, USA.
Nicholas S HillDepartment of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, MA, USA.
Başkent University · TRBoston Medical Center · USCape Cod Healthcare · USJordan Hospital · JOLowell General Hospital · USMorton Hospital · USNewton Wellesley Hospital · USPulmonary Associates · USTufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFew studies have examined locations of noninvasive ventilation (NIV) application for acute respiratory failure (ARF). We aimed to track actual locations of NIV delivery and related outcomes.

methodsObservational cohort study based at 8 acute care hospitals in Massachusetts on adult patients admitted for ARF requiring ventilatory support during pre-determined time intervals.

resultsOf 1225 ventilator starts, 499 were NIV; 209 (42%) in intensive care units (ICU), 185 (37%) in emergency departments (ED), 91 (18%) on general wards, and 14 (3%) in other units. Utilization (% of all ventilator starts) (1), success (2) and in-hospital mortality (3) rates for patients initiated on NIV in ICU, ED, and general and other wards were (1) 38, 36, 73, and 52%, (2) 60, 77, 68, and 93% and (3) 25, 12, 17, and 0%, respectively (p < 0.05 for all). Patients with acute-on-chronic lung disease (ACLD) and acute pulmonary edema (APE) were begun on NIV most often in EDs and patients with 'de novo' ARF and neurologic disorders most often in ICU's. Approximately 2/3 of patients begun on NIV outside of ICUs were transferred within 72 h to ICUs, wards or other units.

conclusionsMost NIV starts occurred in ICUs and EDs but utilization rate was highest (>50%) on general wards where a fifth of NIV starts took place. Actual location depended on etiology of ARF as patients with ACLD and APE were started more often in EDs and "de novo" ARF in ICU. NIV failure and mortality rates were higher in ICUs related to the greater proportion of patients with "de novo" ARF.

Indexed as

Acute DiseaseAgedAged, 80 and overChronic DiseaseEmergency Service, HospitalFemaleHospital MortalityHospitalsHumansIntensive Care UnitsMaleMassachusettsMiddle AgedNervous System DiseasesNoninvasive VentilationPatients' RoomsAcute respiratory failureEmergency careGeneral wardsIntensive care unitsNoninvasive ventilation

Identifiers

PMID26210474
OpenAlexW2260502955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.