Evidence map›Paper›PMID 26210334›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2015

Adolescent Eating Disorders Predict Psychiatric, High-Risk Behaviors and Weight Outcomes in Young Adulthood.

Nadia Micali, Francesca Solmi, Nicholas J Horton, Ross D Crosby, Kamryn T Eddy, Jerel P Calzo, Kendrin R Sonneville, Sonja A Swanson, Alison E Field

Abstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 7 pooled it
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 7 syntheses or guidelines pooled it, 245 citations in OpenAlex.

  1. Associations Between the Use of Fitness and Diet Tracking Technology and Disordered Eating Behaviour: A Systematic Review.European eating disorders review : the journal of the Eating Disorders Association · 2025
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  6. The Follow-Up of Eating Disorders from Adolescence to Early Adulthood: A Systematic Review.International journal of environmental research and public health · 2022
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68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Nadia MicaliInstitute of Child Health, Child and Adolescent Mental Health Palliative Care and Pediatrics Section, University College London, and Icahn School of Medicine at Mount Sinai, New York. Electronic address: n.micali@ucl.ac.uk.
Francesca SolmiUniversity College London.
Nicholas J HortonAmherst College, Amherst, MA.
Ross D CrosbyNeuropsychiatric Research Institute, Fargo, ND, and University of North Dakota School of Medicine and Health Sciences, Fargo.
Kamryn T EddyEating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, and Harvard Medical School, Boston.
Jerel P CalzoDivision of Adolescent Medicine, Boston Children's Hospital and Harvard Medical School.
Kendrin R SonnevilleHuman Nutrition Program, University of Michigan School of Public Health, Ann Arbor.
Sonja A SwansonHarvard School of Public Health, Boston.
Alison E FieldDivision of Adolescent Medicine, Boston Children's Hospital, and Harvard Medical School, Harvard School of Public Health, and Channing Division of Network Medicine, Brigham and Women's Hospital, Boston.
University College London · GBAmherst College · USHarvard University · USMassachusetts General Hospital · USUniversity of Michigan–Ann Arbor · USUniversity of North Dakota · US

Funding

Empirical eating disorder classification and validation using prospective studiesR01MH087786 · NIMH · BROWN UNIVERSITY · PI FIELD, ALISON E · 2010 to 2014
$2.5M
SUBSTANCE USE AND DISORDERED WEIGHT BEHAVIORS IN SEXUAL MINORITY YOUTH CONTEXTSK01DA034753 · NIDA · SAN DIEGO STATE UNIVERSITY · PI CALZO, JEREL PASION · 2013 to 2017
$721k
Medical Research Council 74882Medical Research Council MC_PC_15018NIDA NIH HHS K01 DA034753NIMH NIH HHS MH087786NIMH NIH HHS R01 MH087786Wellcome Trust 076467Wellcome Trust 102215Wellcome Trust 102215/2/13/2
6 · The paper itself

Abstract

objectiveTo investigate whether anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and other specified feeding and eating disorders (OSFED), including purging disorder (PD), subthreshold BN, and BED at ages 14 and 16 years, are prospectively associated with later depression, anxiety disorders, alcohol and substance use, and self-harm.

methodEating disorders were ascertained at ages 14 and 16 years in 6,140 youth at age 14 (58% of those eligible) and 5,069 at age 16 (52% of those eligible) as part of the prospective Avon Longitudinal Study of Parents and Children (ALSPAC). Outcomes (depression, anxiety disorders, binge drinking, drug use, deliberate self-harm, weight status) were measured using interviews and questionnaires about 2 years after predictors. Generalized estimating equation models adjusting for gender, socio-demographic variables, and prior outcome were used to examine prospective associations between eating disorders and each outcome.

resultsAll eating disorders were predictive of later anxiety disorders. AN, BN, BED, PD, and OSFED were prospectively associated with depression (respectively AN: odds ratio [OR] = 1.39, 95% CI = 1.00-1.94; BN: OR = 3.39, 95% CI = 1.25-9.20; BED: OR = 2.00, 95% CI = 1.06-3.75; and PD: OR = 2.56, 95% CI = 1.38-4.74). All eating disorders but AN predicted drug use and deliberate self-harm (BN: OR = 5.72, 95% CI = 2.22-14.72; PD: OR = 4.88, 95% CI = 2.78-8.57; subthreshold BN: OR = 3.97, 95% CI = 1.44-10.98; and subthreshold BED: OR = 2.32, 95% CI = 1.43-3.75). Although BED and BN predicted obesity (respectively OR = 3.58, 95% CI = 1.06-12.14 and OR = 6.42, 95% CI = 1.69-24.30), AN was prospectively associated with underweight.

conclusionsAdolescent eating disorders, including subthreshold presentations, predict negative outcomes, including mental health disorders, substance use, deliberate self-harm, and weight outcomes. This study highlights the high public health and clinical burden of eating disorders among adolescents.

Indexed as

Body WeightAdolescentAnorexia NervosaAnxiety DisordersBinge DrinkingBulimiaBulimia NervosaDepressionFeeding and Eating DisordersFemaleHumansInterview, PsychologicalLongitudinal StudiesMaleMental DisordersProspective StudiesALSPACeating disordersoutcomespsychiatricweight

Identifiers

PMID26210334
PMCPMC4515576
OpenAlexW1569876576

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.