Evidence map›Paper›PMID 26209893›Full record

ReviewImmunology and allergy clinics of North America2015

Eosinophils in Gastrointestinal Disorders: Eosinophilic Gastrointestinal Diseases, Celiac Disease, Inflammatory Bowel Diseases, and Parasitic Infections.

Pooja Mehta, Glenn T Furuta

Abstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Review
  3. Failed Induction of the TIntegrative medicine (Encinitas, Calif.) · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Role of CD34 in inflammatory bowel disease.Frontiers in physiology · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Parasitic Infections of the Gastrointestinal Track and Liver.Gastroenterology clinics of North America · 2021
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pooja MehtaDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Digestive Health Institute, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 East 16th Ave B290, Aurora, CO 80045, USA.
Glenn T FurutaDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Digestive Health Institute, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 East 16th Ave B290, Aurora, CO 80045, USA. Electronic address: glenn.furuta@childrenscolorado.org.

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
TRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Marc E. Rothenberg · 2014 to 2026
$18.5M
Institutional Training Grant in Pediatric GastroenterologyT32DK067009 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI RONALD J. SOKOL, Edwin Fulco de Zoeten · 2005 to 2026
$7.1M
Patient research in eosinophilic gastrointestinal diseasesK24DK100303 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI FURUTA, GLENN T · 2013 to 2017
$889k
NCATS NIH HHS UL1 TR001082NIAID NIH HHS U54 AI117804NIDDK NIH HHS 1K24DK100303NIDDK NIH HHS K24 DK100303NIDDK NIH HHS T32 DK067009
6 · The paper itself

Abstract

The gastrointestinal (GI) tract provides an intriguing organ for considering the eosinophil's role in health and disease. The normal GI tract, except for the esophagus, is populated by eosinophils that are present throughout the mucosa, raising the possibility that eosinophils participate in innate mechanisms of defense. However, data from clinical studies associates increased numbers of eosinophils with inflammatory GI diseases, prompting concerns that eosinophils may have a deleterious effect on the gut. We present clinical features of 4 disease processes that have been associated with eosinophilia and suggest areas requiring investigation as to their clinical significance and scientific relevance.

Indexed as

AnimalsCeliac DiseaseDietEnteritisEosinophiliaEosinophilic EsophagitisEosinophilsGastritisGastrointestinal TractHelminthiasisHelminthsHumansInflammatory Bowel DiseasesIntestinal Diseases, ParasiticPrognosisEosinophilEosinophilic colitisEosinophilic esophagitisEosinophilic gastritisEosinophilic gastroenteritisEsophagitisParasitic infection

Identifiers

PMID26209893
PMCPMC4515563

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.