Evidence map›Paper›PMID 26209439›Full record

ArticleExperimental gerontology2015

Change in motor function and adverse health outcomes in older African-Americans.

Aron S Buchman, Robert S Wilson, Sue E Leurgans, David A Bennett, Lisa L Barnes

Abstract read
In one paragraph

Article in Experimental gerontology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 19 citations in OpenAlex.

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  7. Correlated decline of cognitive and motor phenotypes and ADRD pathologies in old age.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aron S BuchmanRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Neurological Sciences, Rush University Medical Center, United States. Electronic address: Aron_S_Buchman@rush.edu.
Robert S WilsonRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Behavioral Sciences, Rush University Medical Center, United States. Electronic address: rwilson@rush.edu.
Sue E LeurgansRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Neurological Sciences, Rush University Medical Center, United States. Electronic address: Sue_E_Leurgans@rush.edu.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Neurological Sciences, Rush University Medical Center, United States. Electronic address: David_A_Bennett@rush.edu.
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Neurological Sciences, Rush University Medical Center, United States; Department of Behavioral Sciences, Rush University Medical Center, United States. Electronic address: Lisa_L_Barnes@rush.edu.
Rush University Medical Center · US

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1991 to 2020
$49.1M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
The Clinical Profile of Parkinson's Disease (PD) PathologyR01NS078009 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI BUCHMAN, ARON S · 2012 to 2016
$2.4M
NIA NIH HHS P30 AG010161NIA NIH HHS P30AG10161NIA NIH HHS R01 AG022018NIA NIH HHS R01AG22018NINDS NIH HHS R01 NS078009NINDS NIH HHS R01NS78009
6 · The paper itself

Abstract

objectiveWe tested whether declining motor function accelerates with age in older African-Americans.

methodsEleven motor performances were assessed annually in 513 older African-Americans.

resultsDuring follow-up of 5 years, linear mixed-effect models showed that motor function declined by about 0.03 units/year (Estimate, -0.026, p<0.001); about 4% more rapidly for each additional year of age at baseline. A proportional hazard model showed that both baseline motor function level and its rate of change were independent predictors of death and incident disability (all p's<0.001). These models showed that the additional annual amount of motor decline in 85 year old persons at baseline versus 65 year old persons was associated with a 1.5-fold higher rate of death and a 3-fold higher rate of developing Katz disability.

conclusionsThe rate of declining motor function accelerates with increasing age and its rate of decline predicts adverse health outcomes in older African-Americans.

Indexed as

AgedAged, 80 and overAgingBlack or African AmericanDisability EvaluationEducational StatusFemaleFollow-Up StudiesGeriatric AssessmentHumansIllinoisMaleMiddle AgedMotor ActivityMotor DisordersPsychomotor PerformanceAfrican-AmericanAgingDisabilityMortalityMotor decline

Identifiers

PMID26209439
PMCPMC4603389
OpenAlexW938032387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.