Evidence map›Paper›PMID 26208972›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society2015

Mouse anatomy ontologies: enhancements and tools for exploring and integrating biomedical data.

Terry F Hayamizu, Richard A Baldock, Martin Ringwald

Abstract read
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Harmonizing mouse anatomy terminology: a common language?Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  3. Article
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  5. Article
  6. Characterization of individual bile acids in vivo utilizing a novel low bile acid mouse model.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Review
  11. Article
  12. Article
  13. Mouse Genome Informatics (MGI): latest news from MGD and GXD.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Article
  14. Annotated expression and activity data for murine recombinase alleles and transgenes: the CrePortal resource.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Terry F HayamizuThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Richard A BaldockMRC Human Genetics Unit, IGMM, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.
Martin RingwaldThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA. martin.ringwald@jax.org.

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Technical DevelopmentP41HD062499 · NICHD · JACKSON LABORATORY · PI MARTIN RINGWALD · 2011 to 2026
$37.3M
GUDMAP- Database and WebsiteU01DK092983 · NIDDK · UNIVERSITY OF EDINBURGH · PI BALDOCK, RICHARD ALAN · 2011 to 2016
$3.2M
Medical Research Council MC_PC_U127527203Medical Research Council U.1275.2.4.4.1NCI NIH HHS P30 CA034196NICHD NIH HHS HD062499NICHD NIH HHS P41 HD062499NIDDK NIH HHS DK092983NIDDK NIH HHS U01 DK092983
6 · The paper itself

Abstract

Mouse anatomy ontologies provide standard nomenclature for describing normal and mutant mouse anatomy, and are essential for the description and integration of data directly related to anatomy such as gene expression patterns. Building on our previous work on anatomical ontologies for the embryonic and adult mouse, we have recently developed a new and substantially revised anatomical ontology covering all life stages of the mouse. Anatomical terms are organized in complex hierarchies enabling multiple relationships between terms. Tissue classification as well as partonomic, developmental, and other types of relationships can be represented. Hierarchies for specific developmental stages can also be derived. The ontology forms the core of the eMouse Atlas Project (EMAP) and is used extensively for annotating and integrating gene expression patterns and other data by the Gene Expression Database (GXD), the eMouse Atlas of Gene Expression (EMAGE) and other database resources. Here we illustrate the evolution of the developmental and adult mouse anatomical ontologies toward one combined system. We report on recent ontology enhancements, describe the current status, and discuss future plans for mouse anatomy ontology development and application in integrating data resources.

Indexed as

Computational BiologySoftwareAnimalsDatabases, GeneticGene Expression Regulation, DevelopmentalMiceOrgan Specificity

Identifiers

PMID26208972
PMCPMC4602063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.