ArticlePloS one2015
Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Genome-wide association mapping and transcriptional analysis uncover genetic determinants of minor tocopherols in rice seeds.Scientific reports · 2025Article
- Genome-wide association study and genotypic variation for the major tocopherol content in rice grain.Frontiers in plant science · 2024Article
- Role of Tocochromanols in Tolerance of Cereals to Biotic Stresses: Specific Focus on Pathogenic and Toxigenic Fungal Species.International journal of molecular sciences · 2022Review
- Bioactive Compounds and Antioxidant Capacity in Pearling Fractions of Hulled, Partially Hull-Less and Hull-Less Food Barley Genotypes.Foods (Basel, Switzerland) · 2021Article
- Genome-wide association analysis of natural variation in seed tocochromanols of barley.The plant genome · 2020Article
- Molecular Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases.Oxidative medicine and cellular longevity · 2020Review
- Introgression Breeding in Barley: Perspectives and Case Studies.Frontiers in plant science · 2020Review
- Identification of quantitative trait loci for increased α-tocopherol biosynthesis in wild soybean using a high-density genetic map.BMC plant biology · 2019Article
- Deciphering the genetic basis for vitamin E accumulation in leaves and grains of different barley accessions.Scientific reports · 2019Article
- Evidence for Strong Kinship Influence on the Extent of Linkage Disequilibrium in Cultivated Common Beans.Genes · 2018Article
- Vitamin E Biosynthesis and Its Regulation in Plants.Antioxidants (Basel, Switzerland) · 2017Review
- Recent Advances in our Understanding of Tocopherol Biosynthesis in Plants: An Overview of Key Genes, Functions, and Breeding of Vitamin E Improved Crops.Antioxidants (Basel, Switzerland) · 2017Review
- Metabolite profiling of barley flag leaves under drought and combined heat and drought stress reveals metabolic QTLs for metabolites associated with antioxidant defense.Journal of experimental botany · 2017Article
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Genome-Wide Association Studies approach was used to detect Quantitative Trait Loci associated with tocochromanol concentrations using a panel of 1,466 barley accessions. All major tocochromanol types- α-, β-, δ-, γ-tocopherol and tocotrienol- were assayed. We found 13 single nucleotide polymorphisms associated with the concentration of one or more of these tocochromanol forms in barley, seven of which were within 2 cM of sequences homologous to cloned genes associated with tocochromanol production in barley and/or other plants. These associations confirmed a prior report based on bi-parental QTL mapping. This knowledge will aid future efforts to better understand the role of tocochromanols in barley, with specific reference to abiotic stress resistance. It will also be useful in developing barley varieties with higher tocochromanol concentrations, although at current recommended daily consumption amounts, barley would not be an effective sole source of vitamin E. However, it could be an important contributor in the context of whole grains in a balanced diet.
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Registered trials
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