Evidence map›Paper›PMID 26208122›Full record

ReviewCurrent opinion in otolaryngology & head and neck surgery2015

Tinnitus treatment with precise and optimal electric stimulation: opportunities and challenges.

Fan-Gang Zeng, Hamid Djalilian, Harrison Lin

Abstract readReview
In one paragraph

Review in Current opinion in otolaryngology & head and neck surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. [Analysis of intraoperative EABR characteristics and postoperative efficacy of cochlear implant in patients with tinnitus].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Animal Models of Tinnitus Treatment: Cochlear and Brain Stimulation.Current topics in behavioral neurosciences · 2021
    Article
  11. [Effect of cochlear implantation on tinnitus and the prognosis mode analysis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fan-Gang ZengDepartment of Otolaryngology - Head and Neck Surgery and Center for Hearing Research, University of California, Irvine, California, USA.
Hamid Djalilian
Harrison Lin
University of California, Irvine · US

Funding

UC Irvine Core Center for Hearing and Communication ResearchP30DC008369 · NIDCD · UNIVERSITY OF CALIFORNIA-IRVINE · PI ZENG, FAN-GANG · 2007 to 2016
$3.3M
Interactions between Acoustic and Electric StimulationR01DC008858 · NIDCD · UNIVERSITY OF CALIFORNIA-IRVINE · PI ZENG, FAN-GANG · 2007 to 2011
$1.8M
NIDCD NIH HHS P30 DC008369NIDCD NIH HHS P30-DC008369NIDCD NIH HHS R01 DC008858
6 · The paper itself

Abstract

purpose of reviewElectric stimulation is a potent means of neuromodulation that has been used to restore hearing and minimize tremor, but its application on tinnitus symptoms has been limited. We examine recent evidence to identify the knowledge gaps in the use of electric stimulation for tinnitus treatment. RECENT

findingsRecent studies using electric stimulation to suppress tinnitus in humans are categorized according to their points of attacks. First, noninvasive, direct current stimulation uses an active electrode in the ear canal, tympanic membrane, or temporal scalp. Second, inner ear stimulation uses charge-balanced biphasic stimulation by placing an active electrode on the promontory or round window, or a cochlear implant array in the cochlea. Third, intraneural implants can provide targeted stimulation of specific sites along the auditory pathway. Although these studies demonstrated some success in tinnitus suppression, none established a link between tinnitus suppression efficacy and tinnitus-generating mechanisms. SUMMARY: Electric stimulation provides a unique opportunity to suppress tinnitus. Challenges include matching electric stimulation sites and patterns to tinnitus locus and type, meeting the oftentimes-contradictory demands between tinnitus suppression and other indications, such as speech understanding, and justifying the costs and risks of electric stimulation for tinnitus symptoms.

Indexed as

Electric Stimulation TherapyAuditory PathwaysCochlear NerveHumansTinnitus

Identifiers

PMID26208122
PMCPMC4591848
OpenAlexW2215718552

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.