Evidence map›Paper›PMID 26207363›Full record

Observational studyPloS one2015

An Observational Study of the Impact of a Computerized Physician Order Entry System on the Rate of Medication Errors in an Orthopaedic Surgery Unit.

Fabien Hernandez, Elyes Majoul, Carlota Montes-Palacios, Marie Antignac, Bertrand Cherrier, Levon Doursounian, Jean-Marc Feron, Cyrille Robert, Gilles Hejblum, Christine Fernandez and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Fabien HernandezAP-HP, Saint Antoine Hospital, Pharmacy Department, Paris, France.
Elyes MajoulAP-HP, Saint Antoine Hospital, Pharmacy Department, Paris, France.
Carlota Montes-PalaciosAP-HP, Saint Antoine Hospital, Pharmacy Department, Paris, France.
Marie AntignacAP-HP, Saint Antoine Hospital, Pharmacy Department, Paris, France.
Bertrand CherrierAP-HP, Saint Antoine Hospital, Orthopaedic Surgery Department, Paris, France.
Levon DoursounianAP-HP, Saint Antoine Hospital, Orthopaedic Surgery Department, Paris, France.
Jean-Marc FeronAP-HP, Saint Antoine Hospital, Orthopaedic Surgery Department, Paris, France.
Cyrille RobertAP-HP, Saint Antoine Hospital, Anaesthetics and Intensive Care Department, Paris, France.
Gilles HejblumSorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP UMRS 1136), Paris, France.
Christine FernandezAP-HP, Saint Antoine Hospital, Pharmacy Department, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP UMRS 1136), Paris, France; Univ Paris-Sud, Faculty of Pharmacy, Chatenay-Malabry, France.
Patrick HindletAP-HP, Saint Antoine Hospital, Pharmacy Department, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP UMRS 1136), Paris, France; Univ Paris-Sud, Faculty of Pharmacy, Chatenay-Malabry, France.
Sorbonne Université · FRHôpital Saint-Antoine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the impact of the implementation of a Computerized Physician Order Entry (CPOE) associated with a pharmaceutical checking of medication orders on medication errors in the 3 stages of drug management (i.e. prescription, dispensing and administration) in an orthopaedic surgery unit.

methodsA before-after observational study was conducted in the 66-bed orthopaedic surgery unit of a teaching hospital (700 beds) in Paris France. Direct disguised observation was used to detect errors in prescription, dispensing and administration of drugs, before and after the introduction of computerized prescriptions. Compliance between dispensing and administration on the one hand and the medical prescription on the other hand was studied. The frequencies and types of errors in prescribing, dispensing and administration were investigated.

resultsDuring the pre and post-CPOE period (two days for each period) 111 and 86 patients were observed, respectively, with corresponding 1,593 and 1,388 prescribed drugs. The use of electronic prescribing led to a significant 92% decrease in prescribing errors (479/1593 prescribed drugs (30.1%) vs 33/1388 (2.4%), p < 0.0001) and to a 17.5% significant decrease in administration errors (209/1222 opportunities (17.1%) vs 200/1413 (14.2%), p < 0.05). No significant difference was found in regards to dispensing errors (430/1219 opportunities (35.3%) vs 449/1407 (31.9%), p = 0.07).

conclusionThe use of CPOE and a pharmacist checking medication orders in an orthopaedic surgery unit reduced the incidence of medication errors in the prescribing and administration stages. The study results suggest that CPOE is a convenient system for improving the quality and safety of drug management.

Indexed as

Clinical Pharmacy Information SystemsElectronic PrescribingMedical Order Entry SystemsOrthopedic ProceduresHumansMedication ErrorsOrthopedics

Identifiers

PMID26207363
PMCPMC4514799
OpenAlexW2173104390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.