ArticleGut pathogens2015
Virulence characteristics of hcp (+) Campylobacter jejuni and Campylobacter coli isolates from retail chicken.
Article in Gut pathogens, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Antimicrobial and anti-inflammatory properties ofMicrobiology (Reading, England) · 2026Article
- The Missing Pieces: The Role of Secretion Systems inBiomolecules · 2023Review
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- Metaphenotypes associated with recurrent genomic lineages ofFrontiers in microbiology · 2022Article
- AMicrobial genomics · 2021Article
- Mixtures of natural antimicrobials can reduce Campylobacter jejuni, Salmonella enterica and Clostridium perfringens infections and cellular inflammatory response in MDCK cells.Gut pathogens · 2021Article
- Phosphorylation of Extracellular Proteins inFrontiers in microbiology · 2021Article
- Hyper-AerotolerantFrontiers in microbiology · 2021Article
- Bioinformatic Analysis of theFrontiers in microbiology · 2021Article
- Molecular characterization of megaplasmids encoding the type VI secretion system in Campylobacter jejuni isolated from chicken livers and gizzards.Scientific reports · 2020Article
- Virulence Traits of InpatientMicroorganisms · 2020Article
- RevisitingFrontiers in cellular and infection microbiology · 2020Review
- Antimicrobial Resistance and Virulence-Associated Markers inFrontiers in microbiology · 2020Article
- Characterization and Prevalence ofFrontiers in veterinary science · 2020Article
- Attenuation ofMicroorganisms · 2019Article
- Hyper-AerotolerantMicroorganisms · 2019Article
- Role of putative virulence traits of Campylobacter jejuni in regulating differential host immune responses.Journal of microbiology (Seoul, Korea) · 2019Article
- Virulence of a T6SS Campylobacter jejuni chicken isolate from North Romania.BMC research notes · 2019Article
- Clinical impact of the type VI secretion system on virulence of Campylobacter species during infection.BMC infectious diseases · 2019Article
- TheFrontiers in microbiology · 2019Article
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10 authors.
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Abstract
backgroundRecently the Type VI secretion system (T6SS), which can play a significant role in bacterial survival and pathogenesis, was reported in Campylobacter spp., having the hcp gene as a key component.
methodsCampylobacteriosis is associated with the consumption of infected chicken meat. Our study aimed to explore the presence of T6SS in C. jejuni (n = 59) and C. coli (n = 57) isolates, from retail raw chicken and to investigate their pathogenic potential. The hcp gene was used as an indicator for the T6SS presence.
resultsUsing multiplex PCR we have identified a significantly higher prevalence of hcp in C. coli isolates (56.1%) than in C. jejuni (28.8%) and AFLP analysis of the isolates showed a high degree of genetic similarity between the isolates carrying the hcp gene. Genome sequencing data showed that 84.3% of the C. coli and 93.7% of the C. jejuni isolates had all 13 T6SS open reading frames. Moreover, the virulence characteristics of hcp + isolates, including motility and the ability to invade human intestinal epithelial cells in vitro, were significantly greater than in the control strain C. jejuni 12502; a human isolate which is hcp positive.
conclusionOverall, it was discovered that hcp (+) C. coli and C. jejuni isolated from retail chicken isolates posses genetic and phenotypic properties associated with enhanced virulence. However, since human infections with C. coli are significantly less frequent than those of C. jejuni, the relationship between virulence factors and pathogenesis requires further study.
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