Evidence map›Paper›PMID 26206923›Full record

ArticleScience (New York, N.Y.)2015

Precision medicine: Look to the mice.

K C Kent Lloyd, Terry Meehan, Arthur Beaudet, Steve Murray, Karen Svenson, Colin McKerlie, David West, Iva Morse, Helen Parkinson, Steve Brown and 2 more

Abstract readLetter
In one paragraph

Article in Science (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Uses for humanised mouse models in precision medicine for neurodegenerative disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2019
    Review
  3. Review
  4. Recommended housing densities for research mice: filling the gap in data-driven alternatives.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

K C Kent LloydUniversity of California, Davis, Davis, CA 95616, USA. kclloyd@ucdavis.edu.
Terry MeehanEuropean Bioinformatics Institute, Hinxton, Cambridge, CB10 1SD, UK.
Arthur BeaudetBaylor College of Medicine, Houston, TX 77030, USA.
Steve MurrayThe Jackson Laboratory, Bar Harbor, ME 04609, USA.
Karen SvensonThe Jackson Laboratory, Bar Harbor, ME 04609, USA.
Colin McKerlieToronto Centre for Phenogenomics, Toronto, ON, M5T 3H7, Canada.
David WestChildren's Hospital Oakland Research Institute, Oakland, CA 94609, USA.
Iva MorseCharles River Laboratories, Wilmington, MA 01887, USA.
Helen ParkinsonEuropean Bioinformatics Institute, Hinxton, Cambridge, CB10 1SD, UK.
Steve BrownMedical Research Council Harwell, Oxfordshire, OX11 0RD, UK.
Ann-Marie MallonMedical Research Council Harwell, Oxfordshire, OX11 0RD, UK.
Mark MooreInternational Mouse Phenotyping Consortium, Hinxton, Cambridge, CB10 1SD, UK.

Funding

KOMP2-Phase3 Production and Phenotyping by the DTCC Consortium TCP Transfer to UC DavisUM1OD023221 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2016 to 2026
$45.7M
UCD Mutant Mouse Regional Resource CenterU42OD012210 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$29.2M
KOMP Phase II Mouse Production and CryopreservationU42OD011175 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2012 to 2015
$18.9M
High Throughput Production and Cryopreservation of Knockout MiceU42OD011185 · OD · JACKSON LABORATORY · PI MURRAY, STEPHEN A, TAFT, ROBERT A · 2012 to 2015
$17.9M
KOMP Phase II Mouse PhenotypingU54HG006364 · NHGRI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2015
$16.3M
The Jackson Laboratory KOMP2 Phenotyping CenterU54HG006332 · NHGRI · JACKSON LABORATORY · PI BRAUN, ROBERT E, SVENSON, KAREN L · 2011 to 2015
$12.8M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU24DK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2015
$4.1M
Medical Research Council MC_U142684171NHGRI NIH HHS U54 HG006332NHGRI NIH HHS U54 HG006364NIDDK NIH HHS U24 DK092993NIH HHS U42 OD011175NIH HHS U42 OD011185NIH HHS U42 OD012210NIH HHS UM1 OD023221
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Animal ExperimentationAnimalsElectronic Health RecordsFemaleGenomicsHumansMaleMetabolomicsMiceMice, KnockoutNational Institutes of Health (U.S.)Precision MedicineUnited States

Identifiers

PMID26206923
PMCPMC4960978

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.