ArticleEndocrine2016
Hypothalamo-pituitary adrenal axis and sympatho-adrenal medullary system responses to psychological stress were not attenuated in women with elevated physical fitness levels.
Article in Endocrine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Acute Psychological Stress and Pulse Wave Velocity: Meta-Analysis and Recommendations for Future Research.Psychophysiology · 2025Pooled it
- Influence of Regular Physical Activity and Fitness on Stress Reactivity as Measured with the Trier Social Stress Test Protocol: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2018Pooled it
- Is high salt intake inducing obesity via production of cortisol? A novel working hypothesis and pilot study.European journal of nutrition · 2024Trial
- Trial
- Acute hydrocortisone administration reduces cardiovagal baroreflex sensitivity and heart rate variability in young men.The Journal of physiology · 2018Trial
- Association between blood cortisol levels and numerical rating scale in prehospital pain assessment.Communications medicine · 2025Article
- Sociodemographic and clinical factors influencing serum potassium concentration: A retrospective cohort study.Computational and structural biotechnology journal · 2024Article
- Move the night way: how can physical activity facilitate adaptation to shift work?Communications biology · 2024Review
- Changes in stress pathways as a possible mechanism of aerobic exercise training on brain health: a scoping review of existing studies.Frontiers in physiology · 2023Article
- Concepts of Neuroinflammation and Their Relationship With Impaired Mitochondrial Functions in Bipolar Disorder.Frontiers in behavioral neuroscience · 2021Review
- Acute psychosocial stress and working memory performance: the potential of physical activity to modulate cognitive functions in children.BMC pediatrics · 2019Observational
- Metabolic fatigue in resuscitators using personal protection equipment against biological hazard.Investigacion y educacion en enfermeria · 2019Article
- Article
- Subjective Stress, Salivary Cortisol, and Electrophysiological Responses to Psychological Stress.Frontiers in psychology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is not clear if higher levels of cardiorespiratory fitness are associated with lower hypothalamo-pituitary adrenal (HPA) axis and sympatho-adrenal medullary (SAM) system reactivity to psychological stress in women. The association between cardio-metabolic risk markers and acute physiological responses to psychological stress in women who differ in their cardiorespiratory fitness status has also not been investigated. Women with high (n = 22) and low (n = 22) levels of fitness aged 30-50 years (in the mid-follicular phase of the menstrual cycle) were subjected to a Trier Social Stress Test (TSST) at 1500 h. Plasma concentrations of cortisol, adrenaline (Adr), noradrenaline (NA), and dopamine (DA) were measured in samples collected every 7-15 min from 1400 to 1700 h. Heart rate and blood pressure were measured at the same time points. Low-fit women had elevated serum triglyceride, cholesterol/HDL ratio, fasting glucose, and HOMA-IR levels compared with high-fit women. While cortisol, Adr, NA, HR, and blood pressure all demonstrated a significant response to the TSST, the responses of these variables did not differ significantly between high- and low-fit women in response to the TSST. Dopamine reactivity was significantly higher in the low-fit women compared with high-fit women. There was also a significant negative correlation between VO2 max and DA reactivity. These findings suggest that, for low-fit women aged 30-50 years, the response of HPA axis and SAM system to a potent acute psychological stressor is not compromised compared to that in high-fit women.
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Registered trials
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