ReviewThe international journal of cardiovascular imaging2016
Contrast-enhanced ultrasound: clinical applications in patients with atherosclerosis.
Review in The international journal of cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed.
- The cocktail method: influence of microbubble shell homogeneity on acoustic behavior and stability.Soft matter · 2026Article
- Aortic Atherosclerosis: An Updated Review of Current Guidelines and Management Approach-A Literature Review.The International journal of angiology : official publication of the International College of Angiology, Inc · 2026Article
- Translational Nanomedicine and Delivery Tools for Cardiovascular Disease Therapy and Diagnostics.Advances in experimental medicine and biology · 2026Review
- Toward noninvasive optoacoustic imaging of whole-heart dynamics in mice.Light, science & applications · 2025Article
- Echo contrast medium: How the use of contrast echocardiography (ultrasound contrast agents) can improve patient care.World journal of methodology · 2025Review
- Review
- Early Detection of Vulnerable Plaques Using Targeted Biosynthetic Nanobubbles.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Neovascularization in Atherosclerotic Plaques: Clinical Implications, Detection, and Prevention Strategies.Reviews in cardiovascular medicine · 2025Review
- Safety of contrast-enhanced ultrasound using microbubbles in human pregnancy: A scoping review.Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2025Article
- Quantifying Molecular Changes in the Preeclamptic Rat Placenta with Targeted Contrast-Enhanced Ultrasound Imaging.Molecular imaging and biology · 2025Article
- The value of contrast-enhanced ultrasound in assessing carotid plaque vulnerability and predicting stroke risk.Scientific reports · 2025Article
- Contrast-enhanced ultrasound (CEUS): applications from the kidneys to the bladder.Abdominal radiology (New York) · 2024Review
- Diagnostic Methods of Atherosclerotic Plaque and the Assessment of Its Prognostic Significance-A Narrative Review.Journal of cardiovascular development and disease · 2024Review
- Imaging of Carotid Stenosis: Where Are We Standing? Comparison of Multiparametric Ultrasound, CT Angiography, and MRI Angiography, with Recent Developments.Diagnostics (Basel, Switzerland) · 2024Review
- A dual-targeting therapeutic nanobubble for imaging-guided atherosclerosis treatment.Materials today. Bio · 2024Article
- Improving sub-pixel accuracy in ultrasound localization microscopy using supervised and self-supervised deep learning.Measurement science & technology · 2024Article
- Generalized mathematical framework for contrast-enhanced ultrasound imaging with pulse inversion spectral deconvolution.Ultrasonics · 2023Article
- Advances of nanoparticle-mediated diagnostic and theranostic strategies for atherosclerosis.Frontiers in bioengineering and biotechnology · 2023Review
- Contrast-Enhanced Ultrasound Reveals Partial Perfusion Recovery After Hindlimb Ischemia as Opposed to Full Recovery by Laser Doppler Perfusion Imaging.Ultrasound in medicine & biology · 2022Article
- Application of Model-Building Based on Arterial Ultrasound Imaging Evaluation to Predict CHD Risk.Computational and mathematical methods in medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contrast-enhanced ultrasound (CEUS) is increasingly being used to evaluate patients with known or suspected atherosclerosis. The administration of a microbubble contrast agent in conjunction with ultrasound results in an improved image quality and provides information that cannot be assessed with standard B-mode ultrasound. CEUS is a high-resolution, noninvasive imaging modality, which is safe and may benefit patients with coronary, carotid, or aortic atherosclerosis. CEUS allows a reliable assessment of endocardial borders, left ventricular function, intracardiac thrombus and myocardial perfusion. CEUS results in an improved detection of carotid atherosclerosis, and allows assessment of high-risk plaque characteristics including intraplaque vascularization, and ulceration. CEUS provides real-time bedside information in patients with a suspected or known abdominal aortic aneurysm or aortic dissection. The absence of ionizing radiation and safety of the contrast agent allow repetitive imaging which is particularly useful in the follow-up of patients after endovascular aneurysm repair. New developments in CEUS-based molecular imaging will improve the understanding of the pathophysiology of atherosclerosis and may in the future allow to image and directly treat cardiovascular diseases (theragnostic CEUS). Familiarity with the strengths and limitations of CEUS may have a major impact on the management of patients with atherosclerosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.