Evidence map›Paper›PMID 26206313›Full record

ArticleCell research2015

Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation.

Rui Gong, Audrey W Hong, Steven W Plouffe, Bin Zhao, Guangbo Liu, Fa-Xing Yu, Yanhui Xu, Kun-Liang Guan

Abstract readLetter
In one paragraph

Article in Cell research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Review
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  6. Review
  7. Propagating pluripotency - The conundrum of self-renewal.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Review
  8. Article
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  11. 12-Cells · 2022
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui Gong1] Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA [2] Department of Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China [3] Institute of Biomedical Sciences, Shanghai Medical College of Fudan University, Shanghai 200032, China.
Audrey W HongDepartment of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
Steven W PlouffeDepartment of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
Bin ZhaoLife Sciences Institute and Innovation Center for Cell Biology, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Guangbo LiuDepartment of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
Fa-Xing YuChildren's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Yanhui Xu1] Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA [2] Department of Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China [3] Institute of Biomedical Sciences, Shanghai Medical College of Fudan University, Shanghai 200032, China.
Kun-Liang GuanDepartment of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.

Funding

GRADUATE TRAINING IN CELLULAR &MOLECULAR PHARMACOLOGYT32GM007752 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, JOAN HELLER, HANDEL, TRACY M · 1985 to 2023
$13.5M
PROTEIN PHOSPHORYLATION AND GROWTH FACTOR FUNCTIONR01GM051586 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROWN, JOAN HELLER · 1994 to 2024
$7.9M
Regulation of the Hippo pathway and its role in uveal melanomaR01EY022611 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GUAN, KUN-LIANG · 2012 to 2015
$1.5M
NEI NIH HHS EY022611NEI NIH HHS R01 EY022611NIGMS NIH HHS GM51586NIGMS NIH HHS GM7752NIGMS NIH HHS R01 GM051586NIGMS NIH HHS T32 GM007752
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Protein Kinase CAdaptor Proteins, Signal TransducingDiglyceridesEnzyme ActivationHEK293 CellsHumansPhosphoproteinsProtein IsoformsSignal TransductionTranscription FactorsYAP-Signaling ProteinsAdaptor Proteins, Signal TransducingDiglyceridesPhosphoproteinsProtein IsoformsProtein Kinase CTranscription FactorsYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID26206313
PMCPMC4528059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.