Evidence map›Paper›PMID 26205670›Full record

Observational studyBMC research notes2015

Severely deranged vital signs as triggers for acute treatment modifications on an intensive care unit in a low-income country.

Carl Otto Schell, Markus Castegren, Edwin Lugazia, Jonas Blixt, Moses Mulungu, David Konrad, Tim Baker

Erratum issuedOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Essential human and material resources for emergency care in the district hospitals of Burundi.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2023
    Article
  3. Review
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  5. Article
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  7. Review
  8. Article
  9. The global need for essential emergency and critical care.Critical care (London, England) · 2018
    Article
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  11. Article
  12. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Carl Otto SchellCentre for Clinical Research Sörmland, Uppsala University, Uppsala, Sweden. carlottos@hotmail.com.
Markus CastegrenCentre for Clinical Research Sörmland, Uppsala University, Uppsala, Sweden.
Edwin LugaziaDepartment of Anaesthesia and Intensive Care, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Jonas BlixtDepartment of Anaesthesia, Intensive Care and Surgical Services, Karolinska University Hospital, Stockholm, Sweden.
Moses MulunguDepartment of Anaesthesia and Intensive Care, Muhimbili National Hospital, Dar es Salaam, Tanzania.
David KonradDepartment of Anaesthesia, Intensive Care and Surgical Services, Karolinska University Hospital, Stockholm, Sweden.
Tim BakerDepartment of Anaesthesia, Intensive Care and Surgical Services, Karolinska University Hospital, Stockholm, Sweden.
Karolinska University Hospital · SEUppsala University · SEKarolinska Institutet · SEMuhimbili National Hospital · TZMuhimbili University of Health and Allied Sciences · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCritical care saves lives of the young with reversible disease. Little is known about critical care services in low-income countries. In a setting with a shortage of doctors the actions of the nurse bedside are likely to have a major impact on the outcome of critically ill patients with rapidly changing physiology. Identification of severely deranged vital signs and subsequent treatment modifications are the basis of modern routines in critical care, for example goal directed therapy and rapid response teams. This study assesses how often severely deranged vital signs trigger an acute treatment modification on an Intensive Care Unit (ICU) in Tanzania.

methodsA medical records based, observational study. Vital signs (conscious level, respiratory rate, oxygen saturation, heart rate and systolic blood pressure) were collected as repeated point prevalences three times per day in a 1-month period for all adult patients on the ICU. Severely deranged vital signs were identified and treatment modifications within 1 h were noted.

resultsOf 615 vital signs studied, 126 (18%) were severely deranged. An acute treatment modification was in total indicated in 53 situations and was carried out three times (6%) (2/32 for hypotension, 0/8 for tachypnoea, 1/6 for tachycardia, 0/4 for unconsciousness and 0/3 for hypoxia).

conclusionsThis study suggests that severely deranged vital signs are common and infrequently lead to acute treatment modifications on an ICU in a low-income country. There may be potential to improve outcome if nurses are guided to administer acute treatment modifications by using a vital sign directed approach. A prospective study of a vital sign directed therapy protocol is underway.

Indexed as

AdultBlood PressureCritical IllnessDeveloping CountriesDisease ManagementFemaleHeart RateHumansHypotensionHypoxiaIntensive Care UnitsMaleMiddle AgedNurse PractitionersQuality of Health CareRespiratory Rate

Identifiers

PMID26205670
PMCPMC5501369
OpenAlexW2159997747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.