Evidence map›Paper›PMID 26205246›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2015

KnowEnG: a knowledge engine for genomics.

Saurabh Sinha, Jun Song, Richard Weinshilboum, Victor Jongeneel, Jiawei Han

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Envisioning the future of 'big data' biomedicine.Journal of biomedical informatics · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Saurabh SinhaDepartment of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA sinhas@illinois.edu.
Jun SongInstitute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA Department of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Richard WeinshilboumDepartment of Pharmacology, Mayo Clinic, Rochester, MN, USA.
Victor JongeneelInstitute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Jiawei HanDepartment of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
University of Illinois Urbana-Champaign · USMayo Clinic in Arizona · US

Funding

TRAININGU54GM114838 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HAN, JIAWEI, SINHA, SAURABH · 2014 to 2017
$10.8M
INHERITED VARIATIONS IN DRUG-METABOLIZING ENZYMESR01GM028157 · NIGMS · MAYO CLINIC ROCHESTER · PI WEINSHILBOUM, RICHARD M. · 1985 to 2019
$6.9M
NIGMS NIH HHS 1U54GM114838NIGMS NIH HHS R01 GM028157NIGMS NIH HHS U54 GM114838
6 · The paper itself

Abstract

We describe here the vision, motivations, and research plans of the National Institutes of Health Center for Excellence in Big Data Computing at the University of Illinois, Urbana-Champaign. The Center is organized around the construction of "Knowledge Engine for Genomics" (KnowEnG), an E-science framework for genomics where biomedical scientists will have access to powerful methods of data mining, network mining, and machine learning to extract knowledge out of genomics data. The scientist will come to KnowEnG with their own data sets in the form of spreadsheets and ask KnowEnG to analyze those data sets in the light of a massive knowledge base of community data sets called the "Knowledge Network" that will be at the heart of the system. The Center is undertaking discovery projects aimed at testing the utility of KnowEnG for transforming big data to knowledge. These projects span a broad range of biological enquiry, from pharmacogenomics (in collaboration with Mayo Clinic) to transcriptomics of human behavior.

Indexed as

Datasets as TopicGenomicsKnowledge BasesHumansNational Institutes of Health (U.S.)United StatesBD2Kbig datagenomicsNetwork analysisscalable

Identifiers

PMID26205246
PMCPMC5009907
OpenAlexW956820549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.