Trial reportThe Indian journal of medical research2015
Treatment of vitamin D deficiency is an effective method in the elimination of asymptomatic bacterial vaginosis: A placebo-controlled randomized clinical trial.
Trial report in The Indian journal of medical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses.Nutrition & diabetes · 2024Pooled it
- Probiotics reduce the recurrence of asymptomatic bacterial vaginosis in Chinese women.Scientific reports · 2025Trial
- Relationship between vitamin D status and the vaginal microbiome during pregnancy.Journal of perinatology : official journal of the California Perinatal Association · 2019Trial
- Non-linear association between serum vitamin D and bacterial vaginosis in U.S. women: analysis from NHANES 2001-2004.Frontiers in nutrition · 2025Article
- The association between dietary phytochemical index and bacterial vaginosis risk: secondary analysis of case-control study.Journal of health, population, and nutrition · 2024Article
- Effect of 1,25-dihydroxyvitamin D3-glycosides on postpartum health, uterine involution and litter performance of sows in a free farrowing system.Porcine health management · 2023Article
- Association between bacterial vaginosis and 25-Hydroxy vitamin D: a case-control study.BMC infectious diseases · 2023Article
- Alterations of Vaginal Microbiota andMicroorganisms · 2023Review
- Host and Microbiome Interplay Shapes the Vaginal Microenvironment.Frontiers in immunology · 2022Review
- Vitamin D deficiency increases the risk of bacterial vaginosis during pregnancy: Evidence from a meta-analysis based on observational studies.Frontiers in nutrition · 2022Article
- Nutrition in Gynecological Diseases: Current Perspectives.Nutrients · 2021Review
- Strong correlation between urine and vaginal swab samples for bacterial vaginosis.Southern African journal of infectious diseases · 2021Article
- Associations between dietary micronutrient intake and molecular-Bacterial Vaginosis.Reproductive health · 2019Article
- Association of Bacterial Vaginosis with Vitamin D in Pregnancy: Secondary Analysis from the Kellogg Pregnancy Study.AJP reports · 2019Article
- Serum 25-Hydroxyvitamin D and Risk of Self-Reported Bacterial Vaginosis in a Prospective Cohort Study of Young African American Women.Journal of women's health (2002) · 2018Article
- Vitamin D in the Middle East and North Africa.Bone reports · 2018Article
- Serum vitamin D status and bacterial vaginosis prevalence and incidence in Zimbabwean women.American journal of obstetrics and gynecology · 2016Article
- Bacterial Vaginosis Biofilms: Challenges to Current Therapies and Emerging Solutions.Frontiers in microbiology · 2015Review
- Role of Vitamin D in urogenital health of geriatric participants.Journal of mid-life healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesBacterial vaginosis (BV) is the most prevalent vaginal infection in women of reproductive age group which has been found to be associated with vitamin D deficiency. The purpose of this study was to investigate the effectiveness of the administration of 2000 IU/day edible vitamin D for 15 wk to eliminate asymptomatic BV among reproductive age women with vitamin D deficiency.
methodsA total of 208 women with asymptomatic BV, who were found to be eligible after interviews and laboratory tests, were randomly assigned to a control group (n=106) or an intervention group (n=105). They used vitamin D drops daily for 105 days. Vaginal and blood samples were taken before and after the second intervention using identical methods (Nugent score for BV diagnosis, serum 25-hydroxyvitamin D for vitamin D determination).
resultsThe cure rate of asymptomatic BV was 63.5 per cent in the intervention and 19.2 per cent in the control group (P <0.001). The results showed that being unmarried (P=0.02), being passive smoker (P<0.001), and being in the luteal phase of a menstrual cycle during sampling (P=0.01) were significantly associated with post-intervention BV positive results. After these elements were controlled, the odds of BV positive results in the control group was 10.8 times more than in the intervention group (P<0.001). INTERPRETATION &
conclusionsAmong women in reproductive age group with vitamin D deficiency, the administration of 2000 IU/day edible vitamin D was effective in eliminating asymptomatic BV. This treatment could be useful in preventing the symptoms and side effects of BV.
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