ArticleACS applied materials & interfaces2015
Selectively Sized Graphene-Based Nanopores for in Situ Single Molecule Sensing.
Article in ACS applied materials & interfaces, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Graphene Nanopore Fabrication and Applications.International journal of molecular sciences · 2025Review
- Two-dimensional material-based virus detection.Science China. Chemistry · 2022Review
- Nanophotonic biosensors harnessing van der Waals materials.Nature communications · 2021Review
- Gated Single-Molecule Transport in Double-Barreled Nanopores.ACS applied materials & interfaces · 2018Article
- Graphene-edge dielectrophoretic tweezers for trapping of biomolecules.Nature communications · 2017Article
- Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers.Nature communications · 2017Article
- Single Molecule Trapping and Sensing Using Dual Nanopores Separated by a Zeptoliter Nanobridge.Nano letters · 2017Article
- Nanopore extended field-effect transistor for selective single-molecule biosensing.Nature communications · 2017Article
- Substrate Dependent Ad-Atom Migration on Graphene and the Impact on Electron-Beam Sculpting Functional Nanopores.Sensors (Basel, Switzerland) · 2017Article
- Nanopore Sensing.Analytical chemistry · 2017Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The use of nanopore biosensors is set to be extremely important in developing precise single molecule detectors and providing highly sensitive advanced analysis of biological molecules. The precise tailoring of nanopore size is a significant step toward achieving this, as it would allow for a nanopore to be tuned to a corresponding analyte. The work presented here details a methodology for selectively opening nanopores in real-time. The tunable nanopores on a quartz nanopipette platform are fabricated using the electroetching of a graphene-based membrane constructed from individual graphene nanoflakes (ø ∼30 nm). The device design allows for in situ opening of the graphene membrane, from fully closed to fully opened (ø ∼25 nm), a feature that has yet to be reported in the literature. The translocation of DNA is studied as the pore size is varied, allowing for subfeatures of DNA to be detected with slower DNA translocations at smaller pore sizes, and the ability to observe trends as the pore is opened. This approach opens the door to creating a device that can be target to detect specific analytes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.