Trial reportAJR. American journal of roentgenology2015
MRI and CT of Low-Grade Fibromyxoid Sarcoma in Children: A Report From Children's Oncology Group Study ARST0332.
Trial report in AJR. American journal of roentgenology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Application of super-resolution ultrasound in preoperative assessment of axillary low-grade fibromyxoid sarcoma: a case report.Journal of ultrasound · 2026Article
- Localized Thoracic Swelling in a School-Aged Child: Suspected Trauma or Something More Serious? A Case Report.Maedica · 2026Article
- Low-grade fibromyxoid sarcoma of the liver in a pediatric patient: Case report.Radiology case reports · 2025Article
- The role of molecular pathology in soft tissue tumor diagnosis: what the radiologist needs to know.Skeletal radiology · 2025Review
- Case report: Primary pulmonary low grade fibromyxoid sarcoma progressing to dedifferentiation: probably due toFrontiers in oncology · 2024Article
- Thoracoscopic Wedge Resection for Low-Grade Fibromyxoid Sarcoma (Evans Tumor) with Massive Calcification and Originating from the Lung: A Rare Case in an Unexpected Location.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2024Article
- Case report: Primary pleural low-grade fibromyxoid sarcoma in a 4-year-old boy with molecular confirmation.Frontiers in oncology · 2023Article
- Low-grade fibromyxoid sarcoma in the middle ear as a rare location: a case report.Translational pediatrics · 2022Article
- Update of pediatric soft tissue tumors with review of conventional MRI appearance-part 1: tumor-like lesions, adipocytic tumors, fibroblastic and myofibroblastic tumors, and perivascular tumors.Skeletal radiology · 2022Review
- Primary Osseous Low-grade Myxofibrosarcoma of Metatarsal Masquerading as Enchondroma: A Case Report.Journal of orthopaedic case reports · 2022Article
- Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome.Frontiers in pediatrics · 2022Article
- Hybrid Low-Grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma of the Pancreas.Journal of gastrointestinal cancer · 2020Article
- Overview of the clinical and imaging features of the most common non-rhabdomyosarcoma soft-tissue sarcomas.Pediatric radiology · 2019Review
- MRI findings of low-grade fibromyxoid sarcoma: a case report and literature review.BMC musculoskeletal disorders · 2018Review
- Huge mesenteric low-grade fibromyxoid sarcoma: A case report and review of the literature.Rare tumors · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of this article is to determine the MRI and CT features of low-grade fibromyxoid sarcoma in children. MATERIALS AND
methodsWe retrospectively analyzed images of 11 pediatric patients with low-grade fibromyxoid sarcoma from a phase 3 clinical trial of nonrhabdomyosarcoma soft-tissue sarcoma (Children's Oncology Group Protocol ARST0332). MRI and CT were performed in 10 and four patients, respectively. Location, size, margin, and composition on imaging were correlated with pathologic findings.
resultsTumors were located in the extremities in nine patients, and one tumor each was located in the tongue and lung. Tumors were deep in seven patients and superficial in four patients. All tumors were well defined, solitary, and nonmetastatic at presentation. Tumors were complex solid-cystic in eight patients and completely solid in three patients. On T1-weighted images, all tumors had at least some areas hypointense to muscles, and six had a split-fat sign. On STIR or T2-weighted images, eight tumors had areas hypointense to adjacent muscle, and eight tumors had fluid signal intensity. On contrast-enhanced MRI studies, eight tumors had thick enhancing internal septations, and three had peripheral nodular gyriform enhancement. When we correlated imaging to pathologic findings, areas with hypointense signal intensity on both T1- and T2-weighted images were likely related to fibrous component; areas with fluid signal intensity on T2-weighted images were likely related to myxoid component. On CT, all four tumors were hypodense to muscle, and one tumor showed punctate calcific foci.
conclusionLow-grade fibromyxoid sarcoma is hypodense to muscle on CT. MRI may identify both fibrous and myxoid components of this rare pediatric soft-tissue sarcoma.
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