Evidence map›Paper›PMID 26203392›Full record

ArticleBiomedical optics express2015

Non-contact scanning diffuse correlation tomography system for three-dimensional blood flow imaging in a murine bone graft model.

Songfeng Han, Johannes Johansson, Miguel Mireles, Ashley R Proctor, Michael D Hoffman, Joseph B Vella, Danielle S W Benoit, Turgut Durduran, Regine Choe

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  15. Validation of the Linearity in Image Reconstruction Methods for Speckle Contrast Optical Tomography.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Songfeng HanInstitute of Optics, University of Rochester, Rochester, NY 14627, USA.
Johannes JohanssonICFO- Institut de Ciències Fotòniques, 08860, Castelldefels (Barcelona), Spain.
Miguel MirelesICFO- Institut de Ciències Fotòniques, 08860, Castelldefels (Barcelona), Spain.
Ashley R ProctorDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA.
Michael D HoffmanDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA ; Department of Orthopaedics and Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA.
Joseph B VellaDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA ; Department of Orthopaedics and Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA ; Department of Otolaryngology-Head and Neck Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA.
Danielle S W BenoitDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA ; Department of Orthopaedics and Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA ; Department of Chemical Engineering, University of Rochester, Rochester, NY 14627, USA ; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA.
Turgut DurduranICFO- Institut de Ciències Fotòniques, 08860, Castelldefels (Barcelona), Spain.
Regine ChoeDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA ; Department of Electrical and Computer Engineering, University of Rochester, Rochester, NY 14627, USA.
University of Rochester · USInstitute of Photonic Sciences · ESUniversity of Rochester Medical Center · US

Funding

Translating PTH Therapy as an Adjuvant for Structural AllograftingP50AR054041 · NIAMS · UNIVERSITY OF ROCHESTER · PI BRENDAN, BOYCE · 2006 to 2016
$15.7M
Tissue Engineering Strategies to Revitalize Bone AllograftsR01AR064200 · NIAMS · UNIVERSITY OF ROCHESTER · PI Danielle S. Benoit · 2013 to 2026
$4.0M
Training in Orthopaedic Researchhttps://apps.era.nih.gov/grantfolder/viewInternalGF.era?applId=8841318&folderId=90T32AR053459 · NIAMS · UNIVERSITY OF ROCHESTER · PI ZUSCIK, MICHAEL J · 2006 to 2017
$3.4M
The University of Rochester Core Center for Musculoskeletal Biology and MedicineP30AR061307 · NIAMS · UNIVERSITY OF ROCHESTER · PI SCHWARZ, EDWARD M. · 2011 to 2015
$3.0M
Longitudinal monitoring of bone fracture healing using diffuse optical and correlation tomographyR01AR071363 · NIAMS · UNIVERSITY OF ROCHESTER · PI REGINE CHOE · 2017 to 2026
$2.2M
In Vivo Cancer Therapy Monitoring with Diffuse Optical MethodsR00CA126187 · NCI · UNIVERSITY OF ROCHESTER · PI CHOE, REGINE · 2011 to 2013
$710k
In Vivo Cancer Therapy Monitoring with Diffuse Optical MethodsK99CA126187 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHOE, REGINE · 2008 to 2009
$164k
NCI NIH HHS K99 CA126187NCI NIH HHS R00 CA126187NIAMS NIH HHS P30 AR061307NIAMS NIH HHS P50 AR054041NIAMS NIH HHS R01 AR064200NIAMS NIH HHS R01 AR071363NIAMS NIH HHS T32 AR053459
6 · The paper itself

Abstract

A non-contact galvanometer-based optical scanning system for diffuse correlation tomography was developed for monitoring bone graft healing in a murine femur model. A linear image reconstruction algorithm for diffuse correlation tomography was tested using finite-element method based simulated data and experimental data from a femur or a tube suspended in a homogeneous liquid phantom. Finally, the non-contact system was utilized to monitor in vivo blood flow changes prior to and one week after bone graft transplantation within murine femurs. Localized blood flow changes were observed in three mice, demonstrating a potential for quantification of longitudinal blood flow associated with bone graft healing.

Indexed as

(170.0110) Imaging systems(170.3660) Light propagation in tissues(170.6960) Tomography(170.7050) Turbid media

Identifiers

PMID26203392
PMCPMC4505720
OpenAlexW2285474788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.