ArticleBiomedical optics express2015
Optical coherence tomography-based parameterization and quantification of articular cartilage surface integrity.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Detecting human articular cartilage degeneration in its early stage with polarization-sensitive optical coherence tomography.Biomedical optics express · 2020Article
- Quantifying Complex Micro-Topography of Degenerated Articular Cartilage Surface by Contrast-Enhanced Micro-Computed Tomography and Parametric Analyses.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- Quantifying birefringence in the bovine model of early osteoarthritis using polarisation-sensitive optical coherence tomography and mechanical indentation.Scientific reports · 2018Article
- [Chondral and osteochondral defects : Representation by imaging methods].Der Orthopade · 2017Review
- Quantitative OCT and MRI biomarkers for the differentiation of cartilage degeneration.Skeletal radiology · 2016Article
- Detecting early stage osteoarthritis by optical coherence tomography?Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loss of articular cartilage surface integrity is considered the earliest sign of osteoarthritis; however, its reliable detection has not been established by clinical routine diagnostics. This study comprehensively assesses a set of 11 algorithm-based 2-D Optical Coherence Tomography roughness parameters and investigates their clinical impact. Histology and manual irregularity quantification of 105 human cartilage samples with variable degeneration served as reference. The majority of parameters revealed a close-to-linear correlation with the entire spectrum of degeneration. Surface integrity should therefore be assessed by a combination of parameters to improve current diagnostic accuracy in the determination of cartilage degeneration.
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Registered trials
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