Evidence map›Paper›PMID 26203358›Full record

ArticleJournal of pharmaceutical policy and practice2015

Explaining the slow transition of child-appropriate dosage formulations from the global to national level in the context of Uganda: a qualitative study.

Xavier Nsabagasani, Ebba Hansen, Anthony Mbonye, Freddie Ssengooba, Herbert Muyinda, James Mugisha, Jasper Ogwal-Okeng

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Xavier NsabagasaniChild Health and Development Center, College of Health Sciences, Makerere University, P.O. Box 6717, Kampala, Uganda.
Ebba HansenSection for Social and Clinical Pharmacy, Department of Pharmacy, Faculty of Health and Medical Sciences University of Copenhagen, Copenhagen, Denmark.
Anthony MbonyeMinistry of Health Uganda and Department of Health, Uganda Christian University, Kampala, Uganda.
Freddie SsengoobaSchool of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Herbert MuyindaChild Health and Development Center, College of Health Sciences, Makerere University, P.O. Box 6717, Kampala, Uganda.
James MugishaChild Health and Development Center, College of Health Sciences, Makerere University, P.O. Box 6717, Kampala, Uganda.
Jasper Ogwal-OkengDepartments of Pharmacology and Therapeutics, Gulu University, Gulu, Uganda.
Makerere University · UGGulu University · UGMinistry of Health · UGUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2007, the Sixtieth World Health Assembly (WHA) passed a resolution entitled "Better medicines for children" and subsequently the World Health Organization (WHO) recommended the inclusion of child-appropriate dosage formulations in the essential medicines lists of member countries. However, child-appropriate dosage formulations are not highlighted in the Essential Medicines and Health Supplies List of Uganda (EMHSLU) 2012 and they are still limited in availability in public health facilities. Several stakeholders influenced the status of child-appropriate dosage formulations in the EMHSLU 2012.

objectiveTo explore stakeholders' views about the relevance of the globally recommended child-appropriate dosage formulations in the context of Uganda.

methodsThe findings derive from thirty three in-depth interviews with stakeholder representatives and the results of a follow up validation meeting where preliminary findings were shared with stakeholders. Policy analysis and policy transfer theories were used to guide a deductive analysis for manifest and latent content.

resultsAccording to stakeholders, the transition to the globally recommended child-appropriate dosage formulations has been slow in Uganda due to a number of factors. These factors include resource constraints at the global and national levels, lack of Ministry of Health (MOH) formal commitment to the adoption of the child-appropriate dosage formulations policy and a lack of consensus between those who advocated for the availability of liquid oral dosage formulations for easy administration and effectiveness and those who were more convinced by economic arguments and preferred the procurement of solid oral dosage formulations intended for adults.

conclusionsThe global policy for child-appropriate dosage formulations still remains to be implemented in Uganda and other low income countries. This has been due to lack of resources that hindered formal transfer of the policy from the global to the local level. To achieve this transfer there is a need for resource mobilisation at both the international and local levels, together with the revitalisation of UMTAC to enable it to take on a leadership role of the coalitions supporting child-appropriate dosage formulations.

Indexed as

Child-appropriate dosage formulationsChildrenChild size medicines and UgandaPolicy transferStakeholders

Identifiers

PMID26203358
PMCPMC4511518
OpenAlexW2150709273

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.