ReviewJournal of asthma and allergy2015
Early childhood wheezers: identifying asthma in later life.
Review in Journal of asthma and allergy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Association between active tobacco use during pregnancy and infant respiratory health: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Design of the 18-year follow-up of the Danish COPSACBMJ paediatrics open · 2024Article
- Life Course of Asthma.Advances in experimental medicine and biology · 2023Article
- Associations of Early-Life Exposure to Submicron Particulate Matter With Childhood Asthma and Wheeze in China.JAMA network open · 2022Article
- The Association between the Occurrence of Asthma and Antecedents of Exposure to Environmental Tobacco Smoke in the Previous Year in Children: An Incidence-Density Study.International journal of environmental research and public health · 2022Article
- Viral wheezing in early childhood as a risk factor for asthma in young adulthood: A prospective long-term cohort study.Health science reports · 2022Article
- Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification.Journal of personalized medicine · 2021Article
- Proximity to Major Roads and Risks of Childhood Recurrent Wheeze and Asthma in a Severe Bronchiolitis Cohort.International journal of environmental research and public health · 2021Article
- The role of inducible costimulatory molecular ligand (ICOSL) in children with neutrophilic asthma.Translational pediatrics · 2020Article
- Fish oil supplementation during pregnancy is protective against asthma/wheeze in offspring.The journal of allergy and clinical immunology. In practice · 2020Article
- The association of maternal prenatal vitamin D levels and child current wheeze.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018Article
- B7-H3 participates in the development of Asthma by augmentation of the inflammatory response independent of TLR2 pathway.Scientific reports · 2017Article
- Enhanced allergic responsiveness after early childhood infection with respiratory viruses: Are long-lived alternatively activated macrophages the missing link?Pathogens and disease · 2016Article
- Recurrent wheezing in children.Translational pediatrics · 2016Review
- The evaluation of risk factors for recurrent hospitalizations resulting from wheezing attacks in preschool children.Italian journal of pediatrics · 2015Article
- The effect of the indoor environment on wheeze- and sleep-related symptoms in young Indian children.Lung India : official organ of Indian Chest SocietyArticle
- Significant Clinical Associations Between Exposure Type Factors and Recurrent Wheezing and Asthma in Children.Journal of medicine and lifeArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Wheeze in young children is common, and asthma is the most common noncommunicable disease in children. Prevalence studies of recurrent asthma-like symptoms in children under the age of 5 years have reported that one third of children in the US and Europe are affected, and rates and severity appear to be higher in developing countries. Over the last few decades, significant research efforts have focused on identification of risk factors and predictors of wheeze and on tools to identify which children who wheeze will progress to develop asthma. We reviewed the phenotypes of childhood wheezing, genetic risk factors, environmental factors, testing/predictive indices, and primary prevention. While it is generally agreed that a complex interaction of environmental exposure and genetic susceptibility contributes to the development of asthma, limitations in predictive tools and tests restrict our ability to provide families with guidance as to whether their child with wheeze will ultimately develop asthma. Additional research is needed to clarify childhood wheeze phenotypes, to develop tools to determine which children will develop asthma, and to determine how and when to intervene. If these areas can be addressed, it would help reduce this large burden on children, families, and society.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.