Evidence map›Paper›PMID 26202930›Full record

ArticleLeukemia2016

TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia.

S H Tan, A W Y Yam, L N Lawton, R W J Wong, R A Young, A T Look, T Sanda

Open access · greenAbstract readLetter
In one paragraph

Article in Leukemia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. Review
  8. Article
  9. Review
  10. The Genetics and Mechanisms of T-Cell Acute Lymphoblastic Leukemia.Cold Spring Harbor perspectives in medicine · 2020
    Review
  11. The enhancer RNABlood · 2019
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

S H TanCancer Science Institute of Singapore, National University of Singapore, Singapore.
A W Y YamCancer Science Institute of Singapore, National University of Singapore, Singapore.
L N LawtonWhitehead Institute for Biomedical Research, Cambridge, MA, USA.
R W J WongCancer Science Institute of Singapore, National University of Singapore, Singapore.
R A YoungWhitehead Institute for Biomedical Research, Cambridge, MA, USA.
A T LookDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
T SandaCancer Science Institute of Singapore, National University of Singapore, Singapore.
National University of Singapore · SGDana-Farber Cancer Institute · USMassachusetts Institute of Technology · USNational University Cancer Institute, Singapore · SGWhitehead Institute for Biomedical Research · US

Funding

The Molecular Function of D-cyclins in T-ALLP01CA109901 · NCI · DANA-FARBER CANCER INSTITUTE · PI VON BOEHMER, HARALD · 2004 to 2014
$19.6M
Pathway Dependence on Tyrosine Kinase TYK2 in T-cell Acute Lymphoblastic LeukemiaK99CA157951 · NCI · DANA-FARBER CANCER INST · PI SANDA, TAKAOMI · 2011 to 2012
$275k
NCI NIH HHS 1K99CA157951NCI NIH HHS 5P01CA109901NCI NIH HHS K99 CA157951NCI NIH HHS P01 CA109901
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, LeukemicGene Regulatory NetworksBasic Helix-Loop-Helix ProteinsBlotting, WesternCalcium-Calmodulin-Dependent Protein KinasesCell ProliferationGene Expression ProfilingHumansIntracellular Signaling Peptides and ProteinsJurkat CellsNeoplasm ProteinsPrecursor T-Cell Lymphoblastic Leukemia-LymphomaProto-Oncogene ProteinsT-Cell Acute Lymphocytic Leukemia Protein 1Basic Helix-Loop-Helix ProteinsCalcium-Calmodulin-Dependent Protein KinasesIntracellular Signaling Peptides and ProteinsNeoplasm ProteinsProto-Oncogene ProteinsTAL1 protein, humanT-Cell Acute Lymphocytic Leukemia Protein 1TRIB2 protein, human

Identifiers

PMID26202930
PMCPMC4724340
OpenAlexW1906331108

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.