ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2016
Prognostic value of extracardiac incidental findings on attenuation correction cardiac computed tomography.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Clinical significance of incidental findings on coronary CT angiography: Insights from a randomized controlled trial.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Trial
- Looking inside AND outside the heart.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Incidental renal masses on SPECT/CT and PET/CT.American journal of nuclear medicine and molecular imaging · 2022Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2020: positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Incidental findings on cardiac computed tomography: No new emergencies to declare!Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Preventive Cardiology and Risk Assessment: Beyond LDL.Current atherosclerosis reports · 2020Review
- Lurking in the shadows: Asymptomatic bilateral lung involvement with novel corona virus 2019 identified on myocardial perfusion SPECT CT: Implications for interpreting physicians.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Incidental Findings of Malignancy of the Chest by Single Photon Emission Computed Tomography Myocardial Perfusion Imaging (SPECT-CT MPI): One Year Follow-Up Report.Kansas journal of medicine · 2020Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2018. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
- Extracardiac findings on computed tomography attenuation correction: Is it worth paying extra attention?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Multimodality Imaging of Pericardial Diseases.Current treatment options in cardiovascular medicine · 2017Review
- Incidental detection of abnormalJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Review of Cardiovascular Imaging in the Journal of Nuclear Cardiology in 2016. Part 1 of 2: Positron Emission Tomography, Computed Tomography and Magnetic Resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Review
- The good, bad, and ugly of incidental findings on cardiovascular-computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Review of cardiovascular imaging in the journal of nuclear cardiology in 2015. Part 1 of 2: Plaque imaging, positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Review
- Lymph Nodal Plasmacytoma Detected on Myocardial Perfusion Imaging. Revisiting the Past.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAttenuation corrected computed tomography (CTAC) is often performed to improve the specificity of single-photon emission tomography imaging. Extracardiac incidental findings are frequently observed. It is unclear whether these findings have any prognostic value.
methodsConsecutive patients (n = 1139) at a tertiary care center were retrospectively evaluated for incidental findings on CTAC. Clinically significant incidental findings were defined as findings warranting physician follow-up. Information regarding subsequent resource utilization was obtained by chart review. Cox proportional hazard model adjusted for demographic and clinical variables was used to evaluate association of these incidental findings with all-cause and cancer-specific mortality.
resultsA total of 135 (12%) patients with incidental findings were identified, 83 of whom (68%) were newly diagnosed. Lung nodules were the most common finding, present in 92 (68%) patients. Over a median follow-up of 468 days, incidental findings were not significantly associated with increased risk of all-cause mortality (HR 1.34; 95% CI 0.77-2.33, P = 0.29) but was significantly associated with cancer-specific mortality (HR 3.21; 95% CI 1.26-8.14, P = 0.01). This association remained statistically significant when the analysis was limited to newly diagnosed incidental findings. Among patients with incidental findings, follow-up radiographic studies were conducted in 87%, and invasive procedures performed in 32%. Physician office-based follow-up of these findings occurred in 42% of patients and incidental finding-related hospitalization occurred in 14%.
conclusionsThis study shows that incidental findings are common and were associated with all-cause and cancer-specific mortality but only the later remained statistically significant after multivariable adjustment.
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