Evidence map›Paper›PMID 26202680›Full record

ArticleBMC bioinformatics2015

Extending the evaluation of Genia Event task toward knowledge base construction and comparison to Gene Regulation Ontology task.

Jin-Dong Kim, Jung-Jae Kim, Xu Han, Dietrich Rebholz-Schuhmann

Abstract readEvaluation Study
In one paragraph

Article in BMC bioinformatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Large-scale automated machine reading discovers new cancer-driving mechanisms.Database : the journal of biological databases and curation · 2018
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jin-Dong Kim
Jung-Jae Kim
Xu Han
Dietrich Rebholz-Schuhmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe third edition of the BioNLP Shared Task was held with the grand theme "knowledge base construction (KB)". The Genia Event (GE) task was re-designed and implemented in light of this theme. For its final report, the participating systems were evaluated from a perspective of annotation. To further explore the grand theme, we extended the evaluation from a perspective of KB construction. Also, the Gene Regulation Ontology (GRO) task was newly introduced in the third edition. The final evaluation of the participating systems resulted in relatively low performance. The reason was attributed to the large size and complex semantic representation of the ontology. To investigate potential benefits of resource exchange between the presumably similar tasks, we measured the overlap between the datasets of the two tasks, and tested whether the dataset for one task can be used to enhance performance on the other.

resultsWe report an extended evaluation on all the participating systems in the GE task, incoporating a KB perspective. For the evaluation, the final submission of each participant was converted to RDF statements, and evaluated using 8 queries that were formulated in SPARQL. The results suggest that the evaluation may be concluded differently between the two different perspectives, annotation vs. KB. We also provide a comparison of the GE and GRO tasks by converting their datasets into each other's format. More than 90% of the GE data could be converted into the GRO task format, while only half of the GRO data could be mapped to the GE task format. The imbalance in conversion indicates that the GRO is a comprehensive extension of the GE task ontology. We further used the converted GRO data as additional training data for the GE task, which helped improve GE task participant system performance. However, the converted GE data did not help GRO task participants, due to overfitting and the ontology gap.

Indexed as

Gene Expression RegulationGene OntologyGene Regulatory NetworksGenesInformation Storage and RetrievalKnowledge BasesNatural Language ProcessingDatabases, FactualHumansSemantics

Identifiers

PMID26202680
PMCPMC4511578

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.