ArticleEMBO reports2015
BRHIS1 suppresses rice innate immunity through binding to monoubiquitinated H2A and H2B variants.
Article in EMBO reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Regulatory role of epigenetics in rice immunity against bacterial and fungal pathogens.Crop health · 2026Review
- EnP1 exploits H2Aub-dependent epigenetic reprogramming to promote microsporidia proliferation in host cells.PLoS pathogens · 2026Article
- How to improve crop pathogen resistance with epigenetics.Phytopathology research · 2026Review
- Epigenetic weapons of plants against fungal pathogens.BMC plant biology · 2024Review
- Article
- Advances in biological functions and mechanisms of histone variants in plants.Frontiers in genetics · 2023Review
- CaSWC4 regulates the immunity-thermotolerance tradeoff by recruiting CabZIP63/CaWRKY40 to target genes and activating chromatin in pepper.PLoS genetics · 2022Article
- Histone Modification and Chromatin Remodeling During the Seed Life Cycle.Frontiers in plant science · 2022Review
- Priming seeds for the future: Plant immune memory and application in crop protection.Frontiers in plant science · 2022Review
- Comparative Expression Profiling of Snf2 Family Genes During Reproductive Development and Stress Responses in Rice.Frontiers in plant science · 2022Article
- Article
- Multiple functions of SWI/SNF chromatin remodeling complex in plant-pathogen interactions.Stress biology · 2021Review
- Immunity onset alters plant chromatin and utilizes EDA16 to regulate oxidative homeostasis.PLoS pathogens · 2021Article
- Multifaceted Chromatin Structure and Transcription Changes in Plant Stress Response.International journal of molecular sciences · 2021Review
- Exploiting Epigenetic Variations for Crop Disease Resistance Improvement.Frontiers in plant science · 2021Review
- Identification of Histone Modifications Reveals a Role of H2b Monoubiquitination in Transcriptional Regulation ofInternational journal of biological sciences · 2021Article
- Histone Monoubiquitination in Chromatin Remodelling: Focus on the Histone H2B Interactome and Cancer.Cancers · 2020Review
- Plant Histone HTB (H2B) Variants in Regulating Chromatin Structure and Function.Plants (Basel, Switzerland) · 2020Review
- H3K4/K9 acetylation and Lr28-mediated expression of six leaf rust responsive genes in wheat (Triticum aestivum).Molecular genetics and genomics : MGG · 2019Article
- Discovery of Functional SNPs via Genome-Wide Exploration of Malaysian Pigmented Rice Varieties.International journal of genomics · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the absence of pathogen attack, organisms usually suppress immune responses to reduce the negative effects of disease resistance. Monoubiquitination of histone variants at specific gene loci is crucial for gene expression, but its involvement in the regulation of plant immunity remains unclear. Here, we show that a rice SWI/SNF2 ATPase gene BRHIS1 is downregulated in response to the rice blast fungal pathogen or to the defense-priming-inducing compound BIT (1,2-benzisothiazol-3(2h)-one,1, 1-dioxide). The BRHIS1-containing complex represses the expression of some disease defense-related genes, including the pathogenesis-related gene OsPBZc and the leucine-rich-repeat (LRR) receptor-like protein kinase gene OsSIRK1. This is achieved through BRHIS1 recruitment to the promoter regions of target genes through specific interaction with monoubiquitinated histone variants H2B.7 and H2A.Xa/H2A.Xb/H2A.3, in the absence of pathogen attack or BIT treatment. Our results show that rice disease defense genes are initially organized in an expression-ready state by specific monoubiquitination of H2A and H2B variants deposited on their promoter regions, but are kept suppressed by the BRHIS1 complex, facilitating the prompt initiation of innate immune responses in response to infection through the stringent regulation of BRHIS1.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.