Evidence map›Paper›PMID 26202349›Full record

ArticleTransfusion2015

Blood donor deferral for men who have sex with men: the Blood Donation Rules Opinion Study (Blood DROPS).

Brian Custer, Nicolas Sheon, Bob Siedle-Khan, Lance Pollack, Bryan Spencer, Walter Bialkowski, Pam D'Andrea, Marian Sullivan, Simone Glynn, Alan Williams and 1 more

Abstract read
In one paragraph

Article in Transfusion, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Review of Interventions Used to Increase Blood Donor Compliance with Deferral Criteria.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. MSM and blood donation: shifting to individualized risk assessment.Hematology. American Society of Hematology. Education Program · 2023
    Article
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  9. Observational
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  12. Which Infectious Blood Donors Could Be Identified by the Donor History Questionnaire? - Comparison of Blood Donors Infected with HIV or HCV with Notified Cases from General Population in Germany.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2018
    Article
  13. Article
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  17. Should Men who have sex with Men be allowed to donate blood in Israel?Israel journal of health policy research · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brian CusterBlood Systems Research Institute, San Francisco, California.
Nicolas SheonUCSF Center for AIDS Prevention Studies, San Francisco, California.
Bob Siedle-KhanUCSF Center for AIDS Prevention Studies, San Francisco, California.
Lance PollackUCSF Center for AIDS Prevention Studies, San Francisco, California.
Bryan SpencerAmerican Red Cross, New England Region, Dedham, Massachusetts.
Walter BialkowskiBloodCenter of Wisconsin, Milwaukee, Wisconsin.
Pam D'AndreaInstitute for Transfusion Medicine, Pittsburgh, Pennsylvania.
Marian SullivanRTI International, Rockville, Maryland.
Simone GlynnNational Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland.
Alan WilliamsUS Food and Drug Administration, Silver Spring, Maryland.
NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III)

Funding

NHLBI NIH HHS HHSN268201100005I
6 · The paper itself

Abstract

backgroundIn the United States, any man who discloses having had sex with another man (MSM) even once since 1977 is currently deferred from donating blood. A study was conducted to assess noncompliance with the policy at four geographically dispersed blood centers. STUDY DESIGN AND

methodsMale donors 18+ years of age with e-mail addresses were randomly selected and invited to complete a confidential online survey between August and October 2013. No additional recruitment e-mails were sent. Survey content included demographics, sexual history, donation history, compliance with the policy, and opinions about current and modified policies.

resultsResponse rate was 11.5% but varied by center (6.3% to 21.7%). Of 3183 completed surveys, 2.6% of respondents (95% confidence interval, 2.1%-3.2%) reported donation after male-male sex. Noncompliance was not statistically different among the centers (p = 0.1), but was related to age with 5.7, 4.6, 2.5, and 1.0% of donors 18 to 24, 25 to 34, 35 to 54, and 50+ years of age, respectively, reporting noncompliance (p < 0.001). Of all respondents, 6.8% reported at least six female and 0.3% reported at least six male sex partners in the past 5 years. Opinions about the current MSM policy were mixed with noncomplying donors more supportive of change than complying donors. Approximatey half of noncompliers indicated they would adhere to a 1-year deferral.

conclusionNoncompliance with the MSM policy is evident and may be increasing compared to earlier data. Any change from the current policy will require close monitoring to determine whether it affects residual risk of HIV in the US blood supply.

Indexed as

Blood DonorsHomosexuality, MaleAdolescentAdultAgedDonor SelectionFemaleGuideline AdherenceHumansMaleMiddle AgedTime Factors

Identifiers

PMID26202349
PMCPMC4715553

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.