Evidence map›Paper›PMID 26202327›Full record

ArticleBMC psychiatry2015

Broad autism phenotype features of Chinese parents with autistic children and their associations with severity of social impairment in probands.

Li-Juan Shi, Jian-Jun Ou, Jing-Bo Gong, Su-Hong Wang, Yuan-Yue Zhou, Fu-Rong Zhu, Xu-Dong Liu, Jing-Ping Zhao, Xue-Rong Luo

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Li-Juan ShiMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. zijuanwd@163.com.
Jian-Jun OuMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. oujianjun08@163.com.
Jing-Bo GongMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. yefenhua@126.com.
Su-Hong WangMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. yarmine@foxmail.com.
Yuan-Yue ZhouMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. taoyoyo1977@yeah.net.
Fu-Rong ZhuMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. zhufurong1985@126.com.
Xu-Dong LiuDepartment of Psychiatry, Queen's University, 191 Portsmouth Ave, Kingston, ON, K7M 8A6, Canada. liux@queensu.ca.
Jing-Ping ZhaoMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. zhaojingpinghunan@163.com.
Xue-Rong LuoMental Health Institute of the Second Xiangya Hospital and Key Laboratory of Psychiatry and Mental Health of Hunan Province, The Central South University, 139 Middle Renmin Road, Changsha, Hunan, PR China. luoxr@vip.sina.com.
Central South University · CNSecond Xiangya Hospital of Central South University · CNQueen's University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParents of children with autism have higher rates of broad autism phenotype (BAP) features than parents of typically developing children (TDC) in Western countries. This study was designed to examine the rate of BAP features in parents of children with autism and the relationship between parental BAP and the social impairment of their children in a Chinese sample.

methodsA total of 299 families with autistic children and 274 families with TDC participated in this study. Parents were assessed using the Broad Autism Phenotype Questionnaire (BAPQ), which includes self-report, informant-report, and best-estimate versions. Children were assessed using the Chinese version of the Social Responsiveness Scale (SRS).

resultsParents of children with autism were significantly more likely to have BAP features than were parents of TDC; mothers and fathers in families with autistic children had various BAP features. The total scores of the informant and best-estimate BAPQ versions for fathers were significantly associated with their children's SRS total scores in the autism group, whereas the total scores of the three BAPQ versions for mothers were significantly associated with their children's SRS total scores in the TDC group. In the autism group, the total SRS scores of children with "BAP present" parents (informant and best-estimate) were higher than the total SRS scores of children with"BAP absent" parents. In the TDC group, the total SRS scores of children with "BAP present" parents were higher than the total SRS scores of children with"BAP absent" parents (best-estimate).

conclusionsParents of autistic children were found to have higher rates of BAP than parents of TDC in a sample of Chinese parents. The BAP features of parents are associated with their children's social functioning in both autism families and TDC families, but the patterns of the associations are different.

Indexed as

Interpersonal RelationsAsian PeopleAutistic DisorderChildChild DevelopmentChild, PreschoolFathersFemaleHumansMaleMothersPhenotypePhysical ExaminationSelf ReportSurveys and Questionnaires

Identifiers

PMID26202327
PMCPMC4511534
OpenAlexW2122445564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.